Month: September 2020

Mutation at Codon 249 of the TP53 Gene in Hepatocellular Carcinoma: MD-CT and Pathologic Features

1. Abstract Aflatoxin B1 is a mycotoxin produced by the Aspergillus Flavus fungus that contaminates many sources of food. This mycotoxin has its metabolism into the liver. So, Aflatoxin B1 metabolites create a DNA mutation at the third base of codon 249 in the TP53 tumor suppressor gene, inducing a G to T trasversion (AGG …

Mutation at Codon 249 of the TP53 Gene in Hepatocellular Carcinoma: MD-CT and Pathologic Features Read More »

High-Dose Methotrexate, A Tried-and-True Treatment with Genomic Delicacies: A Case Report

1. Abstract The prediction of methotrexate (MTX) adverse events has been a challenge to the clinician; here we present a case of toxicity after the previous exposition with the development of hepatic, renal, and hematologic toxicity. The development of methotrexate toxicity has been previously analyzed in our institution, where a significant percentage of the patients …

High-Dose Methotrexate, A Tried-and-True Treatment with Genomic
Delicacies: A Case Report
Read More »

Predictive Factors of Bowel Resection Due to an Incarcerated Groin Hernia

1. Abstract 1.1. Purpose: In this retrospective study, we assessed factors that can be used to predict the need for bowel resection due to an incarcerated groin hernia. 1.2. Methods: We enrolled a total of 83 patients diagnosed with an incarcerated groin hernia on preoperative unenhanced Computed Tomography (CT) between January 2010 and December 2019 …

Predictive Factors of Bowel Resection Due to an Incarcerated Groin Hernia Read More »

Gut-Liver Axis Modulation: A Potential Role of Probiotics and Omega-3 Fatty Acids in Management of NAFLD

1. Abstract Non-Alcoholic Fatty Liver Disease (NAFLD) has currently emerged as common liver disorder com- pared to alcoholic liver disease. The prevalence of NAFLD in India varies from 9% in rural areas to 32% in urban populations. This incidence is reported to be the lowest in western India (44.1%) compared to the highest prevalence in …

Gut-Liver Axis Modulation: A Potential Role of Probiotics and Omega-3 Fatty Acids in Management of NAFLD Read More »

Emergency Care Sick Palliative and Problems Oncology in Emergency Department during the Covid-19 Pandemic

1. Abstract Emergency medical care in palliative patients during the COVID-19 pandemic, it is important to provide a consistent treatment for stable patients that should be consistent with the goals and benefits, the perspective of these patients, but avoiding palliative patients with a poor prognosis that is unlikely to survive. Cancer is the second leading …

Emergency Care Sick Palliative and Problems Oncology in Emergency
Department during the Covid-19 Pandemic
Read More »

Principles of Cryopreservation and Applicabilities in Intestinal Organoids

1. AbstractCryobiology is known as a study of low temperatures effects in tissues and cells, which means understand influences on decreasing temperature and pressure in the freezing medium and how the cell membrane reacts to these variables. Cryopreservation emerged by the principles of Cryo- biology as a technology capable of preserving the composition and viability …

Principles of Cryopreservation and Applicabilities in Intestinal Organoids Read More »

Evidence to the Empirical: A Novel Clinical Score to Predict Spontaneous Bacterial Peritonitis (SBP) in Patients of Chronic Liver Disease Using Ascitic Fluid (AF) Ap- pearance, Symptoms & Severity of Cirrhosis

1. Abstract 1.1. Background and objectives: Ascitic fluid cell count is definitive to diagnose SBP. Timely availability of cell count is crucial, especially in peripheral setting. Study aims to identify reliable predicting factors and to arrive at a a five point Novel Non- invasive clinical score for SBP in CLD which in turn provides evidence …

Evidence to the Empirical: A Novel Clinical Score to Predict Spontaneous Bacterial Peritonitis (SBP) in Patients of Chronic Liver Disease Using Ascitic Fluid (AF) Ap- pearance, Symptoms & Severity of Cirrhosis Read More »