Month: December 2020

Hepatitis B Virus X Protein and Hepatitis C Virus Core Protein Cooperate to Inhibit P16 Expression Via DNA Methylation

1. Abstract Coinfection with hepatitis B virus (HBV) and hepatitis C virus (HCV) is often associated with a higher risk of hepatocellular carcinoma (HCC). Here, we found that HBV X protein (HBx) and HCV core protein cooperate to inhibit p16 expression via DNA methylation in human hepatoma cells. For this purpose, they additively upregulated both …

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Proximal Esophageal Anchored Stent: A Successful Endoscopic Approach in A “Troublesome” Location

1. Case Report A 71-year-old woman was admitted for the surgical treatment of a pulmonary adenocarcinoma of the right upper lobe. During anesthesia induction, a left Robertshaw endotracheal tube (ETT) was inadvertently placed in the esophagus. After successful bronchoscopic ETT repositioning, the patient underwent an uneventful VATS (Video-Assisted Thoracoscopic Surgery) right upper lobectomy and lymphadenectomy. …

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Immune Profile of Severe Refractory Crohn’s Disease Patients Candidates to Autologous Hematopoietic Stem Cell Transplantation

1. Abstract Crohn’s disease is a chronic relapse – remitting inflammatory bowel disease with a wide range of incapacitating symptoms, and significant health care costs. The complex pathophysiology of Crohn’s disease is not always solved by conventional and biologic therapies and thus, some patients evolve with severe refractory disease. T and B cells reacting to …

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Synchronous Colitis Induced by Hot Water Enema-An Easily Missed Etiology for Colitis in Modern Days

1. Abstract 1.1. Background: Colitis caused by hot water was not seen frequently in the past, however, in recent times it is increasingly seen in the clinic. Colitis caused by hot water might be associated with complications such as rectal burn, permanent rectal stricture and bowel perforation, and even death [1]. 1.2. Aims: Colitis caused …

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Assessment of Muscle and Fat Mass in Type 2 Diabetes Patients By Dual-Energy X-Ray Absorptiometry

1. Abstract 1.1. Background: The aim of this study was to assess the quantitative composition of muscle and adipose tissue in type 2 diabetes mellitus (T2DM) patients on the basis of dual-energy X-ray absorptiometry for the diagnosis of obesity and sarcopenia. 1.2. Methods: Dual-energy X-ray absorptiometry was administered to 50 patients with T2DM. Evaluation of …

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Pneumobilia

1. Clinical Image A 71-year-old man presented to the emergency department with a seven-day history of intermittent fever, middle and right upper abdominal pain, and general malaise. The physical examination of the abdomen was normal. Ten years ago he underwent open cholecystectomy and stone removal from common bile duct by endoscopic retrograde cholangiopancreatography (ERCP). At …

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High THC Oil in Ulcerative Colitis: A Case Report

1. Abstract Here we presented the case of a 48-year-old patient affected by lumbosacral pain treated with high concentrated THC cannabis oil. He suffered also from ulcerative colitis (UC), whose symptoms were poorly controlled by non-steroidal anti-inflammatory drugs (NSAIDs). During the cannabis oil treatment, the patient reported a significant relief from irritable bowel syndrome (IBS) …

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An Adult Acute Epiglottis Case Diagnosed During Upper Gastrointestinal Endoscopy and Possibly Related to Hookah Smoking

1. Introduction Acute epiglottitis has the potential to cause sudden, complete airway obstruction. It is a medical emergency that requires rapid diagnosis and careful management of the airway. Although infrequent in adult patient group, if overlooked, it has the potential for the worse outcomes. We present a case of acute epiglottitis which in the routine …

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Concurrent Gastric Hyperplastic and Fundic Gland Polyps in a Patient Taking Proton-Pump Inhibitor

1. Clinical Image A 61-year-old man presented with iron-deficiency anemia (hemoglobin, 8.1 g/dl). He had been taking warfarin and low-dose aspirin for atrial fibrillation and post mitral valve replacement. He had also taken 15 mg lansoprazole daily for 6 years for treatment of gastroesophageal reflux disease. Serum anti-Helicobacter pylori IgG antibody and H. pylori testing …

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Colon Versus Rectal Cancers among Surgical Approach: An Observational Study

1. Abstract 1.1. Background: Colorectal cancer is the most common tumor of the gastrointestinal tract, and it is the third leading cause of mortality throughout the world. 1.2. Objectives: An observational study of colorectal cancers. 1.3. Methods: The research was carried out in Abu Ghraib General hospital in the period from January 2019 to May …

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