Sorafenib-Induced Exosome Secretion Promotes Chemotherapy Resistance in Hepatoma Cell Line
1. Abstract Hepatocellular Carcinoma (HCC) is a most common cause of cancer- related deaths globally. Traditional HCC treatments, including surgery, radiation therapy, and chemotherapy, could provide potential options; however, Sorafenib has been used for advanced HCC treatment. Unfortunately, most patients with advanced-stage HCC do not benefit from Sorafenib for its easy progression to resistance. Although …