Submit Manuscript now
Impact Factor 2.6

Month: August 2022

Role of TGF-Β in Colorectal Cancer: Mechanisms, Diagnosis and Therapies

Leave a Comment / Issue 1 Articles, Volume 9 / By

1. Abstract Colorectal cancer (CRC) is a substantial public health challenge across the globe. Transforming growth factor-β (TGF-β) is a critical pathway in CRC that regulate numerous cellular processes, including immune-suppression, growth inhibition, cell migration, invasion, epithelial-to-mesenchymal transition and extracellular matrix remodeling. Metastasis is the major cause of death in patients with colorectal cancer. TGF-β …

Role of TGF-Β in Colorectal Cancer: Mechanisms, Diagnosis and Therapies Read More »

Epidemiology of Small Gastrointestinal Stromal Tumors and Survival Outcomes Due To Surgical Options: A SEER-Based Population Retrospective Study

Leave a Comment / Issue 1 Articles, Volume 9 / By

1. Abstract 1.1. Background: There is a dearth of population-based evidence regarding the role of surgery in the treatment of patients with small gastrointestinal stromal tumors (sGISTs)(<2cm). The purpose of this study was to describe the demographic features and investigate the impact of surgery treatment on survival outcome in patients with sGISTs.

DBPR108, A Dipeptidyl Peptidase-4 Inhibitor for Treatment of Type 2 Diabetes Mellitus: A Phase I, Randomized, Double-Blind, Placebo-Controlled Trial of Single and Multiple Doses in Healthy Volunteers

Leave a Comment / Issue 1 Articles, Volume 9 / By

1. Abstract 1.1. Aims DBPR108 is an orally active dipeptidyl peptidase 4 (DPP-4) inhibitor in animals. The present first-in-human randomized, double-blind, and placebo-controlled study evaluated DBPR108 for safety and tolerability in healthy adult Asian male volunteers. 1.2. Main Methods DBPR108 were orally given at 25-600 mg as single and multiple once-daily doses for 8 consecutive …

DBPR108, A Dipeptidyl Peptidase-4 Inhibitor for Treatment of Type 2 Diabetes Mellitus: A Phase I, Randomized, Double-Blind, Placebo-Controlled Trial of Single and Multiple Doses in Healthy Volunteers Read More »

Partial Splenic Embolization for the Treatment of Thrombocytopenia in Cancer Patients

Leave a Comment / Issue 1 Articles, Volume 9 / By

1. Abstract Thrombocytopenia is a common sequela of chemotherapy treatment of many non-hematologic malignancies. Severe thrombocytopenia may necessitate halting chemotherapy or lead to hemorrhagic complications that impact patient morbidity and mortality. Partial Splenic Embolization (PSE) has been shown to be effective at improving platelet counts in appropriately selected patients and allowing for the resumption of …

Partial Splenic Embolization for the Treatment of Thrombocytopenia in Cancer Patients Read More »

Management of Hyperacute Rejection during Operation in Living Donor Liver Transplantation – A Case Report

Leave a Comment / Issue 1 Articles, Volume 9 / By

1. Abstract Hyperacute rejection in solid organ transplantation is a catastrophic event and leads to graft failure immediately. It rarely happens in liver transplantation during operation. A 58-year-old male patient had salvage living donor liver transplantation for recurrent hepatocellular carcinoma. His wife was the donor. All the transplantation procedures were uneventful until bile duct anastomosis …

Management of Hyperacute Rejection during Operation in Living Donor Liver Transplantation – A Case Report Read More »

Identification of Pyroptosis-Related Subtypes in Liver Cancer, Establishment of Prognostic Models, and Characterization of Tumor Microenvironment Infiltration

Leave a Comment / Issue 1 Articles, Volume 9 / By

1. Abstract 1.1. Objectives: Pyroptosis is a type of programmed cell death that has been discovered and confirmed in recent years, which were characterized by pro-inflammatory and is related to tumor progression, prognosis and treatment response. However, the potential roles of pyroptosis-related genes (PRGs) in the tumor microenvironment (TME) remain unclear. At the same time, …

Identification of Pyroptosis-Related Subtypes in Liver Cancer, Establishment of Prognostic Models, and Characterization of Tumor Microenvironment Infiltration Read More »

Clinical Relevance of Bile Acid and their Conjugates in Health and Disease

Leave a Comment / Issue 1 Articles, Volume 9 / By

1. Short Communication Bile Acids (BA) are synthesized by the oxidation of cholesterol in the liver and secreted into the duodenum. BAs were circulated from the duodenum back to the liver by enterohepatic recirculation. BAs regulate many physiological functions, including the expression of genes involved cholesterol, glucose, and their homeostasis. BAs have several pathologic effects, …

Clinical Relevance of Bile Acid and their Conjugates in Health and Disease Read More »

Comparative Efficacy and Safety of Polyethylene Glycol vs Lactulose in Chronic Constipation: Non Inferiority Study

Leave a Comment / Issue 1 Articles, Volume 9 / By

1. Abstract 1.1. Background: Constipation is a common condition. Lactulose & Polyethylene Glycol (PEG) are effective & safe, recommended as first-line medication for Chronic Constipation (CC). 1.2. Aim: To compare the efficacy and safety of PEG 3350 versus lactulose in patients with CC. 1.3. Methods: In this single-center, randomised, open label, parallel-group study. Patients with …

Comparative Efficacy and Safety of Polyethylene Glycol vs Lactulose in Chronic Constipation: Non Inferiority Study Read More »

Pulmonary Pleura Metastasis from Low-Grade Appendiceal Mucinous Neoplasm with Appendiceal Neuroendocrine Tumor: A Case Report and Literature Review

Leave a Comment / Issue 1 Articles, Volume 9 / By

1. Abstract Low-grade Mucinous Appendiceal Neoplasm (LAMN) is a rare appendiceal tumor and has low malignant potential. LAMN and Appendiceal Neuroendocrine Tumor (ANET) are the most frequent benign and malignant appendiceal lesions. A collision between LAMN and Appendiceal neuroendocrine tumor (ANET)is an exceedingly rare condition. So far, evaluating the literature, just 10 cases of collision …

Pulmonary Pleura Metastasis from Low-Grade Appendiceal Mucinous Neoplasm with Appendiceal Neuroendocrine Tumor: A Case Report and Literature Review Read More »

What Our Author Say's

I am glad that I found this platform. It was easy to get my research published and I was guided at every step. I highly recommend them.
Shuang-Qin Yi
am grateful to the Japanese Journal of Gastroenterology and Hepatology for helping me with my research and publishing it. Looking forward to more work with them.
Makki Fayadh
It has been a pleasure working with the Japanese Journal of Gastroenterology and Hepatology. They have been amazing in helping me with my manuscript
Han Min
I am glad that I submitted my manuscript here. They helped me make necessary edits and published the best version of it. I highly recommend them.
Sadaf Saleem

FAQ's About Jajgastrohepto

The Japanese Journal of Gastroenterology and Hepatology accepts all kinds of manuscripts, such as research, studies, reviews, clinical images, editorials, commentaries, etc.

For Detailed quotations reach out submission@jajogh.jp

It depends on the length of the manuscript and the reviews and edits needed.

We will help you with as many reviews and edits as are required to make your manuscript perfect for publication.

A good impact factor for JJGH is 2.0 as per Journal Citations Reports of 2021.

Niigata, 7F Stork Building Kagamibashi, 1230-7, 7-bancho, Kamiookawamaedori, Chuo-ku, Niigata, 951-8068, Japan.

*2021 Journal unofficial Impact Factor was established by dividing the number of articles published in 2020 with the number of times they are cited in 2021 based on Google Scholar Citation Index database. If ‘X’ is the total number of articles published in 2020 and ‘Y’ is the number of times these articles were cited in indexed journals during 2021 then, journal impact factor = Y/X.

Copyright 2018-2024 All Rights Reserved.