Roles and Signaling Pathways of CITED1 in Tumors: Overview and Novel Insights
1. Abstract CBP/p300 interacting trans activator with Glu/Asp‑rich car boxy‑terminal domain 1 (CITED1) is a transcription activator belongs to a member of the non-DNA-binding transcription co-regulator family. It regulates diverse transcriptions by binding to CBP/p300 co-activators through its conserved trans activating domain CR2, including TGF-β/BMP-SMAD, estrogen, Wnt-β-catenin and androgen-AR signaling pathways. CITED1 not only plays …
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