Month: October 2023

Degenerated Peutz-Jeghers Syndrome with Peritoneal Carcinomatosis: A Case Report and Overview of a Rare Disease

1. Abstract Peutz-Jeghers syndrome (PJS) is a genetic disease with dominant au- tosomic transmission, characterized by the development of hamar- tomatous polyps in the digestive tract, associated with muco-cutane- ous pigmentation. PJS is a serious condition that can be life threaten- ing due to the significant increase of cancer risk.

Tumor Microenvironment and Immune System in Early-Stage Breast Cancer: Distinct Pathways for Early Recurrence Following Mastectomy and Chemotherapy in Ductal and Lobular Types of the Disease

1. Abstract 1.1. Background: Intra-ductal cancer (IDC) is the most common type of breast cancer, with intra-lobular cancer (ILC) coming in second. Surgery is the primary treatment for early stage breast cancer. There are now irrefutable data demonstrating that the immune context of breast tumors can influence growth and metastasis. Adjuvant chemotherapy may be administered …

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Corrosive Stricture in Oral Cavity- A Rare Presentation

1. Abstract 1.1. Introduction: Corrosive injury of the upper gastrointestinal tract has been commonly reported in medical literature. It can be due to ingestion of acid or alkali and may be accidental or suicidal. The extent of injury varies from involving the esophagus, stomach, and duodenum either individually or together but oral cavity is rarely …

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Effects of Acupuncture on Body Mass Index in Overweight/Obese Women with Polycystic Ovary Syndrome: Study Protocol for a Randomized Controlled Trial

1. Abstract 1.1. Background: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy among reproductive-aged women, characterized by endocrine, metabolic and psychological features. Weight management is recommended as a first-line treatment for PCOS. Acupuncture is assumed to be an effective and safe treatment for reducing weight.

Prevention of Hepatitis-B Reactivation During Immunosuppressive Therapy, Chemotherapy, Treatment with Biological Agents and After Organ Transplantation

1. Introduction Hepatitis B virus (HBV) is a major health problem worldwide. It is estimated that one in 3 persons have been exposed to HBV and around 400 million have chronic HBV.[1, 2] In Saudi Arabia the prevalence of HBV markers before implementation of HBV immunization (1990) was reported to be 50% for a single …

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Treatment of Wilson Disease in Japan: An Insurance Claims Database Study

1. Abstract 1.1. Background & Aims: Wilson disease (WD) is a rare hereditary disease of copper metabolism. For such rare diseases, analysis of health insurance claims databases allows data collection from large numbers of patients. The objective of this study was to evaluate the characteristics and treatment of patients with WD in Japan using the …

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