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Aggressive Cholecystitis Mimicking Gallbladder Cancer

1. Abstract Xanthogranulomatous cholecystitis (XGC) is a benign uncommon variant of chronic cholecystitis. Perioperative findings may lead to confusion with gallbladder cancer, as the inflammation frequently extends to adjacent organs. In this report, we present a 50-year-old woman with a 2- years history of chronic abdominal pain and imaging suggestive of gallbladder carcinoma. The pathological …

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Endpoint Selection and Serum Markers in Clinical Trials of New Drugs for Hepatitis B Cure

1. Abstract Chronic hepatitis B virus (HBV) infection leads to a heavy disease burden globally, which is disproportionately high in Asia Pacific region. The currently available antiviral therapy can effectively suppress HBV replication but is not capable of eliminating the virus. Many new drugs aiming at HBV cure are under investigation in recent years, most …

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