Therapy for the Hepatitis C Virus (HCV) has undergone a revolution with the introduction of Direct-Acting Antivirals (DAA). DAAs achieve Sustained Virological Response (SVR) in 90-95% of treated patients, compared to 50-70% of those receiving dual pegylated interfere on and ribavir in therapy
Aortoenteric Fistula (AEF) is a rare cause of massive gastrointestinal bleeding. Primary AEF are rare and generally the consequence of an aortic aneurysm. The duodenum and esophagus are the main locations of AEF. Diagnosis is difficult and patients are often hemodynamically unstable at the time of management because
Gastro-Oesophageal Varices (GOV) in the presence of liver fibrosis along with splenomegaly on USS abdomen are used as surrogate markers of portal hypertension for grading intestinal failure associated liver disease (IFALD). The severity of IFALD determines the type of intestinal transplant performed
Hepatocellular carcinoma is the most common primary malignant tumor of the liver. Cirrhosisis associated with its carcinogenesis, so periodic surveillance is necessary. Ultrasonography is currently the most appropriate test for screening hepatocellular carcinoma, and alpha-fetoprotein is the most used biomarker despite its low sensitivity
Abdominal cocoon syndrome, the idiopathic form of sclera sing encapsulating peritonitis, is a rare condition of unknown etiology that results in an intestinal obstruction due to total or partial encapsulation of the small bowel by a fibro collage nous membrane (cocoons) [1]. A major challenge faced by clinicians while dealing with this entity is that
FSince the discovery of the Hepatitis B Surface Antigen [1] and recognition of the antigen linked with post-transfusion hepatitis by the same group and others, significant progress on our understanding of the Hepatitis B Virus (HBV) has followed. Such advances include the illustration of the HBV virion [2], identification of Hepatitis B e-Antigen [3]
Inflammatory Bowel Disease (IBD) are the manifestation of overzealous dysregulated immune response in the intestinal tract, directed primarily against the indigenous microbes combined with defective functioning of anti-inflammatory pathways. Finding a trustable lead to predicting de novo Crohn’s Disease (CD)
Inflammatory Bowel Disease (IBD) is recklessly evolving worldwide as incautious disaster, especially in developing nations as a regional duplicitous emergence disease. It has come to light that adaptive Western culture, rapid urbanization lifestyle in the developing nations have been seen
Formaldehyde (FA) is a common environmental pollutant that can cause serious liver damage. The aim of this study is to investigate the effect of FA on cholesterol metabolism in human hepato cellular carcinoma cells (HepG2). After exposure to different concentrations of FA for 24 and 48 h, free cholesterol (FC) contents
Patients with plasma LDL values lower than 80 mg/dL were collected into the first, lower than 100 mg/dL into the second, lower than 130 mg/dL into the third, lower than 150 mg/dL into the fourth, and 150 mg/dL and higher into the fifth groups, respectively
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