Volume 5

Predictive Factors of Decompensation and Death in 670 Patients with Hepatitis C Treated with Direct-Acting Antivirals

1. Abstract Sustained virological response 12 weeks after treatment (SVR12) with direct-acting antivirals (DAAs) is excellent in patients with hepatitis C but little has been published regarding decompensation and/or death during therapy. 1.1. Objectives: Objectives of this prospective, observational, multicenter study were to describe SVR12 in real life patients with advanced fibrosis/cirrhosis treated with DAAs …

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Synchronous Triple Colorectal Cancer with Intestinal Obstruction in an Elderly Patient: Rare Case of Malignancy of the Large Intestine

1. Clinical Image Synchronous cancers are characterized by the simultaneous occurrence of multiple primary tumors in the same patient. Synchronous malignancies most commonly occur in the colon, with a high prevalence in elderly patients [1,2]. The occurrence of synchronous colorectal cancers is extremely rare and may be identified at any location within the large intestine …

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Menghini Needles are Superior to Tru-Cut Needles for Blind Percutaneous Liver Biopsy in Children

1. Abstract 1.1. Background: Liver biopsy remains the criterion standard in the evaluation of the etiology and extent of disease of the liver. Various needles are available for use, depending on the approach and on physician experience. 1.2. Methods: We used in our service for three years Menghini needles and the last year Tru- cut …

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Chicken Bone Perforation of Duodenum

1. Abstract Ingestion of foreign bodies is a common clinical problem encountered commonly in children and elderly people wearing dentures. It is rarely seen in adults. Complications due to ingested bone fragments are not common and preoperative diagnosis remains a challenge. We report a successful endoscopic management of a chicken bone piece which was perforating …

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Spectrum of Acute Hepatitis B at Tertiary Care Center of Northeren India

1. Abstract 1.1. Introduction: Hepatitis is often a viral infection and Hepatitis B Virus (HBV) is reason in significant proportion of cases worldwide. Hepatitis B virus impact on liver can be of varying severity ranging from acute hepatitis to chronic hepatitis which can further lead to chronic liver disease, liver cirrhosis and hepatocellular carcinoma (HCC). …

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Role of Serum Nitric Oxide in Prediction of Hepatocellular Carcinoma in Hepatitis CPatients Treated with Direct – Acting Antiviral Agents

1. Abstract1.1. Background: Hepatocellular Carcinoma (HCC) is the 6th most common malignancy globally and it’s the most common tumor which originates primarily in the liver, the aim of this study is to find out the connection between increased serum nitric oxide (sNO) and its HCC predictive value in patients who received direct-acting antiviral agents (DAAs).1.2. …

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Oropharyngeal Transition during Swallowing between Stroke and Head and Neck Cancer Survivors

1. Abstract 1.1. Objective: The purpose of this study was to analyze three oropharyngeal bolus transition timings, Oral Transition Time (OTT), Pharyngeal Transition Time (PTT), and Duration of Upper Esophageal Sphincter Opening (DUESO), using videofluoroscopic swallowing examinations (VFSEs) between stroke survivors and head and neck cancer survivors to determine differences between the two populations. 1.2. …

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Large Bowel Auto-Immune Diseases: Current Recommendation for Surgery

1. Abstract There are two clinical features of autoimmune disease in the large intestine that we often find in our clinical practice, including ulcerative colitis and Crohn’s Disease. The clinical picture that we need to understand is the change in bowel patterns over the past few weeks. Clinical symptoms that appear need to be diagnosed …

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Alagille Syndrome: Not Always Hepatic Involvement

1. Clinical Image We present a 22-month-old girl affected by surgical palliative corrected Tetralogy of Fallot and peculiar facial features characterized by prominent forehead, deep-set eyes, pointed chin and bulbous tip of nose (Figure 1) typical of Alagille Syndrome (AS). Hypoplasia of the distal phalanges of both feet and two butterfly vertebrae at D10-D11 on …

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More Than Meets the Eyes – An Unusual Aetiology for Pan-Proctocolitis

1. Clinical Presentation A middle-age gentleman, residing in Singapore, presented with altered bowel habits for 2-week duration, associated with left iliac fossa pain, hematochezia and significant weight loss of 10kg. There was no significant travel history or sick contact preceding the symptoms. Physical examination was unremarkable, except for digital rectal examination which revealed in duration …

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