Research Article

Adverse Event Severity Grading System Applied to Percutaneous Transhepatic Biliary Metal Stenting as A One- or Two-Stage Procedure in Patients with Unresectable Malignant Extrahepatic Bile Duct Obstruction

1. Abstract 1.1. Aims: Percutaneous transhepatic biliary stenting (PTBS) can be associated with adverse events (AEs) of different severities. AEs might be assessed by a standardized AE severity grading system. The aim of this study was to compare the severity of adverse events in the 30-day interval after PTBS as a one- or two-stage procedure …

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The Use of Inhalational Nitrous Oxide (Entonox) As The Sole Analgesic Agent During Colonoscopy is Feasible and Efficacious in a Substantial Proportion of Patients: A Review of a Surgeon’s Experience

1. Abstract 1.1. Objective: Colonoscopy is associated with significant discomfort requiring administration of intravenous (IV) sedation and analgesia. Nitrous Oxide (Entonox) has been shown as an alternative analgesic modality but is less frequently used in practice. This study examined the efficacy and applicability of Entonox as sole analgesic agent during colonoscopy. DOI:http://dx.doi.org/10.47829/JJGH.2021.62202

Synthesis, Characterization, Biological Evaluation of Some Heterocyclic Oxazepine Derivatives

1. Abstract The new serious of pentyloxy and aryloxy benzaldehyde (3ae) were synthesized from the substitution reaction of 4-hydroxy benzaldehyde with different aryl bromide and alkyl bromide, on the basis of Williamson ether synthesis in the presence of Potassium carbonate using absolute ethanol as a solvent. The second step was the synthesis of 2-amino-5-(p-tolyl)1,3,4-thiadiazole. DOI:http://dx.doi.org/10.47829/JJGH.2021.62201

Mixing of Sputnik V and Astrazeneca COVID-19 Vaccines

1. Abstract The coronavirus disease 2019 (COVID-19) vaccine helps to develop immunity to SARS-CoV-2, the virus that causes COVID-19, in most cases preventing the disease. Although various brands of vaccines work in different modes, all COVID-19 vaccines prompt an immune reaction to make the body remembers how to protect from the virus in the future. …

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Increased Expression of GNL3L is Associated with Aggressive Phenotypes in Colorectal Cancer

1. Abstract 1.1. Background and Objective: Guanine nucleotide binding protein-like 3-like (GNL3L) plays critical roles in development and progression of several types of human cancers. However, the function and clinical significance of GNL3L in colorectal cancer (CRC) remain unclear. In this study, the effect of GNL3L in CRC and its underlying mechanism were investigated. DOI:http://dx.doi.org/10.47829/JJGH.2021.62103

Review of Esophagectomy Side Effects

1. Abstract The primary indication for an esophagectomy is esophageal cancer or Barrett’s esophagus with high-grade dysplasia. Patients undergoing esophagectomy often present with dysphagia, side effects from chemotherapy, decreased appetite, and weight loss. Esophagectomy may be an operation involving the abdomen, neck, and/or chest requiring 5 to 7 days of NPO status to permit healing …

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Need of Dual Antiviral Treatment in Chronic Hepatitis B

1. Abstract 1.1. Introduction: Approximately one third of the world’s population has serological evidence of past or present infection with the hepatitis B virus (HBV). An estimated 350-400 million people are surface HBV antigen (HBsAg) carriers. India has 40 million HBV carriers i.e. 10–15% share of total pool of HBV carriers of the world. In …

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