Research Article

1. Abstract 1.1. Background: Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) is a transcription factor that regulates the expression of the cellular antioxidant response. Traditionally, Nrf2 is regarded as a tumor suppressor owing to its characteristic which prevents oxidative or electrophilic insult. However, there is increasing evidence that Nrf2 is activated in malignant cells. At …

Effects of Targeting NRF2 on Inhibiting Gastric Cancer Growth and Tumor Development in Vitro and in Vivo Read More »

1. Abstract 1.1. Background: Colorectal cancer liver metastases (CRLM) that cannot be surgically removed are often addressed locally with Hepatic Arterial Infusion (HAI) or Selective Internal Radiation Therapy (SIRT). This study used Bayesian network meta-analysis (NMA) to assess the differences in survival between patients treated with HAI or SIRT for CRLM.

1. Abstract 1.1. Background: Colorectal cancer liver metastases (CRLM) that cannot be surgically removed are often addressed locally with Hepatic Arterial Infusion (HAI) or Selective Internal Radiation Therapy (SIRT). This study used Bayesian network meta-analysis (NMA) to assess the differences in survival between patients treated with HAI or SIRT for CRLM.

1. Abstract 1.1. Background: Anemia represents a significant problem in Inflammatory Bowel Disease (IBD) and diagnosis may be challenging due to inflammation. Hepcidin, ferroportin and hephaestin are novel Iron Regulatory Proteins (IRPs) involved in iron metabolism. This study aimed to identify the interactions of these proteins in IBD patients, guiding safe iron supplementation and effective …

Hepcidin, Ferroportin and Hephaestin Levels in Inflammatory Bowel Disease; Are they Key Mediators of Anemia or Inflammation? Read More »

1. Abstract 1.1. Background: Colorectal cancer (CRC) is the third most common and the fourth most lethal type of cancer. Current therapies for CRC mainly include chemotherapy, radiotherapy, and surgery. However, the therapeutic effects of these therapies are not satisfactory for advanced CRC patients.

1. Abstract 1.1. Introduction: Covid-19 is a global pandemic around the world and entered India in March,2020 and has led to substantial morbidity and mortality till date. There had been many drug trials all over world for it but, many time treatment strategies have been revised in different parts of world, including India but still …

Can Hepatitis B Virus Inhibit Covid-19 Virus Read More »

1. Abstract 1.1. Background: Yindan Pinggan Capsule, a patent Chinese medicine, has a definite effect on Yang Huang syndrome. At present, the pharmacological activity and quality control of Yindan Pinggan Capsule have been studied, but its effective constituents on the treatment of Yang Huang syndrome are still unclear.

1. Abstract 1.1. Background: The burden of Gastroesophageal reflux disease is high among the Saudi population. Various defense mechanisms play a role in preventing GERD, and the usefulness of manometry in identifying them has not been studied well in Saudi Arabia.

1. Abstract 1.1. Background: Bcylcholinesterase (BCHE) is a nonspecific esterase synthesized by the liver that promotes cell proliferation and differentiation. Several studies suggested that BCHE is related to the occurrence and development of some tumors. However, the expression of BCHE in stomach adenocarcinoma (STAD) and its regulatory mechanism remains elusive.