Research Article

1. Abstract Hepatocyte transplantation for acute liver failure and metabolic liver disorders represent a potential alternative to traditional orthotopic liver transplantation (OLT). Additionally, cultured primary hepatocytes are an important tool for in vitro pharmacological studies. Advances in clinical hepatocyte transplantation and drug studies depend on the development of standardized isolation and culturing protocols as well …

Primary Murine Hepatocyte Isolation and Culture with GMP and Research-Grade Enzyme Blends Read More »

1. Abstract 1.1. Aim: The objective of study reported here was to evaluate the clinical efficacy, side effects and long survival time in the advanced stages of all solid tumors after the treatment of UMIPIC. 1.2. Methods: 581 patients with solid tumors in late stages were collected for retrospect analysis of their clinical efficacy, adverse …

Acute Tumor Inflammation with CD4/8+ and CD11+ Enhanced Long Survival Time in Advanced Stages of all Solid tumors by Ultra Minimum Incision Personalized Intratumoral Chemoimmunotehrapy Read More »

1. Abstract 1.1. Aims: The purpose of this study was to describe Portosystemic Cannulation (PSC) Under Ultrasound (US) guidance to perform a Transjugular Intrahepatic Portosystemic Shunt (TIPS) placement. 1.2. Methods: Medical records of 23 patients who underwent TIPS procedure with US-guided PSC at our institute between October 2018 to December 2021 were reviewed, including for …

Ultrasound-Guided Portosystemic Cannulation During Transjugular Intrahepatic Portosystemic Shunt Placement: An Experience of 23 Cases Read More »

1. Abstract 1.1. Background Endoscopic ultrasonography (EUS) has become a reliable method for predicting the invasion depth of early gastric cancer (EGC). However, diagnostic accuracy of EUS is affected by several factors. In particular, it is difficult to differentiate between T1a and T1b EGC through EUS. The aim of this study was to confirm whether …

Diagnostic Evaluation of Endoscopic Ultrasonography with and without Submucosal Saline Injection for Differentiating Between T1a and T1b Early Gastric Cancer Read More »

1. Abstract 1.1. Background Oncological survival after operation of resectable pancreatic ductal adenocarcinoma (R-PDAC) is variable depending on various factors. Preoperative risk stratification could guide decision-making in multidisciplinary treatment concepts. We develop and validate a prognostic score for disease-free survival (DFS) in R-PDAC to solve this issue.

1. Abstract 1.1. Background and Objetive: Irritable bowel syndrome (IBS) is presented as a biopsychosocial model according to Rome criteria. In Chile there are not studies on psychosocial risk factors (PRF) in IBS. The aim was to evaluate PRF in patients with IBS and their relationship with clinical severity, phenotypes and associated pathologies. 1.2. Methods …

Psychosocial Risk Factors in Chilean Patients with Irritable Bowel Syndrome Read More »

1. Abstract 1.1. Purpose To study the survival time of mice with tumor by intratumoral injection with chemotherapy drug Adr plus hapten of DNP or Hydra and find a combination of drugs of Adr with DNP or Hydra can prolong their life, and which one of DNP or Hydra can provide a long life extension …

Acute Tumor Inflammation with CD4/8+ and CD11+ Prolong The Survival Effect Induced by Intratumral Injection Optimum Combination of Chemotherapy Drugs with Hydralazine as Hapten in Animal Model Read More »

1. Abstract 1. Aims: This study aims to compare the HR-QoL among rural Chinese patients with upper GI diseases at different pathological stages and to determine the factors influencing HR-QoL in this population. 1.2. Methods: A cross-sectional survey was conducted in two counties in Shandong province in China from July to September 2018. Demographic and …

Health-Related Quality of Life Among Rural Chinese Patients with Upper Gastrointestinal Diseases at Different Pathological Stages: A Cross-Sectional Study Read More »

1. Abstract 1.1. Background: Hepatitis C (HCV) is a serious public health problem with approximately 3% of the world’s population infected. Patients on chronic hemodialysis are known to be a population at risk of HCV infection worldwide. 1.2. Aims: This study aimed to estimate the serological prevalence of HCV and characterize the HCV viral load …

Prevalence and Characterization of Hepatitis C infection and Determination of Liver Damage in Patients on Chronic Hemodialysis at the Largest Reference Center for Renal Health, EsSalud, Lima, Peru Read More »

1. Abstract 1.1. Background: Gastric cancer is often associated with anaemia, at the time of diagnosis, which may contribute to worse outcomes after surgery. This study aims to evaluate the impact of preoperative anaemia and the need of perioperative transfusions in surgical and oncological outcomes among patients undergoing gastric cancer surgery. 1.2. Methods: This single …

The Influence of Anaemia and Perioperative Blood Transfusion in The Outcomes of Gastric Cancer Read More »