Research Article

1. Abstract 1.1. Background: Ampullary cancer is of particular classificatory interest as it may arise either from the intestinal epithelium or the epithelium covering the pancreatobiliary ducts knows as Intestinal type (IT) and Pancreatobiliary type (PBT) respectively. These 2 histological subtypes have different clinical characteristics, in terms of disease stage, recurrence rates and survival. Immuno …

Role of Immunohistochemically Typing in Pancreaticobiliary and Intestinal Type Differentiation of Periampullary Adenocarcinomas Read More »

1. Abstract 1.1. Introduction: It is important to determine the epidemiological factors like etiology, age, sex, mode of clinical presentation of fatty liver and development of complications like chronic liver disease, so as to design optimal and cost effective preventive and treatment strategies for the same.

1. Abstract 1.1. Introduction: Hepatitis B Virus (HBV) infection is a global problem with nearly 350 million chronic carriers, who are at risk of liver cirrhosis & hepatocellular carcinoma. Over 50% of these carriers are believed to have acquired their infection vertically from their mothers, i.e. through mother – to – Child Transmission (MTCT). Vertically …

Effective Strategies for Preventing Vertical Transmission in Hepatitis B Read More »

1. Abstract 1.1. Background and Aim The epidemiology, clinical characteristics, natural course, and treatment of Inflammatory Bowel Disease (IBD) in the gastroenterology centres of Al Kharj, Riyadh Province, are still largely unknown. Therefore, a survey was conducted to describe IBD features to correlate the findings with published data from the rest of the country and …

Inflammatory Bowel Disease in a Central Rural Area, Riyadh Province Al-Kharj of Saudi Arabia: Epidemiology, Clinical Characteristics, Natural Course of Disease and Current Clinical Practice Read More »

1. Abstract 1.1. Background: We evaluated the changes of biomarkers and their significance in patients with nonalcoholic fatty liver disease. 1.2. Methods: One hundred and ten nonalcoholic fatty liver disease patients were enrolled into experimental group and one hundred and ten healthy people into control group. The plasma levels of biomarkers were detected. 1.3. Results: …

Changes of Plasma Biomarkers in Patients with Chronic Liver Diseases Predict Liver Cell Death Read More »

1. Abstract Hepatocyte transplantation for acute liver failure and metabolic liver disorders represent a potential alternative to traditional orthotopic liver transplantation (OLT). Additionally, cultured primary hepatocytes are an important tool for in vitro pharmacological studies. Advances in clinical hepatocyte transplantation and drug studies depend on the development of standardized isolation and culturing protocols as well …

Primary Murine Hepatocyte Isolation and Culture with GMP and Research-Grade Enzyme Blends Read More »

1. Abstract 1.1. Aim: The objective of study reported here was to evaluate the clinical efficacy, side effects and long survival time in the advanced stages of all solid tumors after the treatment of UMIPIC. 1.2. Methods: 581 patients with solid tumors in late stages were collected for retrospect analysis of their clinical efficacy, adverse …

Acute Tumor Inflammation with CD4/8+ and CD11+ Enhanced Long Survival Time in Advanced Stages of all Solid tumors by Ultra Minimum Incision Personalized Intratumoral Chemoimmunotehrapy Read More »

1. Abstract 1.1. Aims: The purpose of this study was to describe Portosystemic Cannulation (PSC) Under Ultrasound (US) guidance to perform a Transjugular Intrahepatic Portosystemic Shunt (TIPS) placement. 1.2. Methods: Medical records of 23 patients who underwent TIPS procedure with US-guided PSC at our institute between October 2018 to December 2021 were reviewed, including for …

Ultrasound-Guided Portosystemic Cannulation During Transjugular Intrahepatic Portosystemic Shunt Placement: An Experience of 23 Cases Read More »

1. Abstract 1.1. Background Endoscopic ultrasonography (EUS) has become a reliable method for predicting the invasion depth of early gastric cancer (EGC). However, diagnostic accuracy of EUS is affected by several factors. In particular, it is difficult to differentiate between T1a and T1b EGC through EUS. The aim of this study was to confirm whether …

Diagnostic Evaluation of Endoscopic Ultrasonography with and without Submucosal Saline Injection for Differentiating Between T1a and T1b Early Gastric Cancer Read More »

1. Abstract 1.1. Background Oncological survival after operation of resectable pancreatic ductal adenocarcinoma (R-PDAC) is variable depending on various factors. Preoperative risk stratification could guide decision-making in multidisciplinary treatment concepts. We develop and validate a prognostic score for disease-free survival (DFS) in R-PDAC to solve this issue.