1. Abstract 1.1. Background: Various colonoscopic bowel preparations are in use clinically. Split-dose preparations are generally recommended for morning colonoscopies. We herein present a novel form of bowel preparation with split-dose lactulose as the backbone with oral bisacodyl and sodium phosphate, in a pilot study assessing its safety and efficacy.
1. Abstract 1.1. Introduction: Anticancer drug insensitivity/resistance is a bottleneck in the treatment of gastric cancer. To overcome this challenge, we evaluated the clinical utility of an in-vitro collagen gel droplet embedded culture drug sensitivity test (CD-DST) using patient-derived gastric cancer tissues for personalized treatment guidance. 1.2. Methods: We collected the surgically removed fresh tumor …
1. Abstract 1.1. Background: Tubercular appendicitis is a rarely encountered entity, even in developing country like India where tuberculosis (TB) is highly prevalent. 1.2. Case Report: A 26-year-old female patient presented initially with short duration epigastric pain associated with intermittent vomiting and mimicked non ulcer dyspepsia (NUD). The pain later became more intense, generalized and …
1. Abstract 1.1. Background: The blood is a life saving component which cannot be produced but has to donated by healthy donors. In view of high Seroprevalence of transfusion-transmitted infectious diseases such as HIV, hepatitis B virus (HBV), hepatitis C virus (HCV) and syphilis in India which affects the safety of blood for recipients, mandatory …
Tele Counseling -Effective Strategy for Blood Donors with Chronic Hepatitis B and C Read More »
1. Abstract 1.1. Aim: To explore whether the teach-back health education model can reduce the incidence of malnutrition during radiotherapy in pa- tients with locally advanced esophageal cancer. 1.2. Methods: A historical study design was used to compare the in- cidence of malnutrition during radiotherapy between the traditional education model and the teach-back health education …
1. Abstract Immunogenic Cell Death (ICD) plays an important role in the treatment of colorectal cancer, and the relevant molecular mechanisms of its role in colorectal cancer are closely related to a variety of Damage-Associated Molecular Patterns (DAMPs), such as calreticulin (CRT), Heat Shock Protein (HSP), Adenosine Triphosphate (ATP), high mobility group protein B1 (HMGB1) …
Expression Mechanism of Immunogenic Cell Death-Related Molecules in Colorectal Cancer Read More »
1. Abstract 1.1. Background: This study was intended to investigate the effect of different infusion rates of human serum albumin on 30-day survival of neonatal capillary leak syndrome. 1.2. Methods: We retrospectively retrieved data from electronic medical records at our children’s hospital and we included all the term new-borns admitted between October 2017 to October …
Effect of Rapid Intravenous Albumin Infusion in Neonate with Capillary Leak Syndrome Read More »
1. Abstract CBP/p300 interacting trans activator with Glu/Asp‑rich car boxy‑terminal domain 1 (CITED1) is a transcription activator belongs to a member of the non-DNA-binding transcription co-regulator family. It regulates diverse transcriptions by binding to CBP/p300 co-activators through its conserved trans activating domain CR2, including TGF-β/BMP-SMAD, estrogen, Wnt-β-catenin and androgen-AR signaling pathways. CITED1 not only plays …
Roles and Signaling Pathways of CITED1 in Tumors: Overview and Novel Insights Read More »
1. Abstract 1.1. Background: Plexiform fibromyxoma is a rare mesenchymal tumor of the stomach, found almost exclusively in the antrumor pylorus regions. 1.2. Case Presentation: We incidentally found a protruding mucosal lesion in an asymptomatic 38-year-old man upon gastroscopy. The lesion was located in the upper gastric body, with mucosal plica disruption. An abdominal computed …
Plexiform Fibromyxoma Is A Rare Benign Gastric Tumor: A Case Report Read More »
1. Abstract Colorectal cancer (CRC) is a substantial public health challenge across the globe. Transforming growth factor-β (TGF-β) is a critical pathway in CRC that regulate numerous cellular processes, including immune-suppression, growth inhibition, cell migration, invasion, epithelial-to-mesenchymal transition and extracellular matrix remodeling. Metastasis is the major cause of death in patients with colorectal cancer. TGF-β …
Role of TGF-Β in Colorectal Cancer: Mechanisms, Diagnosis and Therapies Read More »
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