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Severe Hereditary Hemochromatosis Due to Heterozygous H63D Mutation: Unusual Presentation

1. Abstract 1.1. Introduction Diagnosis of hereditary hemochromatosis is based on molecular sequencing of the HFE gene in search for one of the three most frequent mutations: p.Cys282Tyr (C282Y); p.His63Asp (H63D) and pSer65Cys (S65C). Iron overload linked to the H63D mutation especially in the heterozygous state is not conventionally considered significant enough to cause the …

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An Adolescent with Vomiting and Weight Loss

1. Abstract Pediatric Achalasia is a rare condition in children, often presents with common symptoms of vomiting and weight loss. We present a case of a 15-year-old female with persistent vomiting and weight loss who was initially diagnosed with eosinophilic esophagitis (EoE) due to endoscopic findings and elevated eosinophils on esophageal histology

Elevated Pre-chemotherapy Plasma High D-dimer Levels Affect Survival of Advanced Gastric Cancer: An analysis of propensity score

1. Abstract 1.1. Background: Gastric cancer is a prevalent malignancy of the digestive system. There are presently no efficacious indicators to evaluate its curative effect and prognosis. Increased plasma D-dimer was researched to have a really deep connection between neoplasm in advanced stages and bad Overall Survival (OS) for some malignancies in distinct rates.

Atopic Dermatitis is a Multi-Organ Disorder Disease Involving Not Only the Skin but also the Intestinal Tract

1. Introduction Based on test data, we have experienced cases in which atopic dermatitis patients have a high multi-antigen positive rate, which is not seen in patients with allergic diseases such as bronchial asthma and allergic rhinitis. In addition, we often encounter patients with atopic dermatitis who have exorbitant IgE levels. In addition, it is …

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