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Rs1310191201(C>T) Polymorphism in 3‘UTR of BIRC5promote Carcinogenesis of Human Gastric Cancer by De-Regulation by Mir-330-5p in Chinese Population

1. Abstract Previous reports have revealed that down-regulation of miR-330-5p expression can promote os- teosarcoma growth and invasion by targeting oncogene Baculoviral IAP repeat-containing pro- tein 5 (BIRC5). However, the function of the single nucleotide polymorphism (SNP) located in the 3’UTR of BIRC5 regulated by miR-330-5p has not been investigated in human Gastric Can- cer …

Rs1310191201(C>T) Polymorphism in 3‘UTR of BIRC5promote Carcinogenesis of Human Gastric Cancer by De-Regulation by Mir-330-5p in Chinese Population Read More »

Rapid SARS-Cov-2 Infection Spreading within a Family Cluster: The Importance of Gastro-Intestinal Symptoms

1. Abstract 1.1. Background: In Phase-2 COVID-19 pandemic, timely control of new outbreaks is pivotal to avoid an epidemic rebound. A better knowledge of clinical disease profiles and the development of sensitive diagnostic flow charts will help to take more effectiveactions. 1.2. Patients and Methods: We studied an outbreak occurred in 3 families during a …

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Bcl-2 and SIRT3 Affect Tumor Cell Viability by Integrating Metabolism and Apoptosis

While apoptotic tolerance caused by B cell lymphoma 2 (Bcl-2) over expression is one of the important underlying mechanisms of the decreased apoptotic sensitivity of tumor cells, only tar- geting Bcl-2 as an anticancer therapy has shown limited clinical benefit, which may be related to the non-apoptotic protective effects of Bcl-2, such as its roles …

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Undertreatment of Hepatitis C Virus Infection in Elective Total Hip Arthroplasty

Total Hip Arthroplasty (THA) in patients with hepatitis C virus (HCV) are known for poor outcomes increased risk of iatrogenic infection. New Direct Antiviral Agents (DAA) can now cure HCV infection. However, undertreatment is still common in patients undergoing THA. Our aim was to assess the prevalence of HCV infection and treatment rates inpatients with …

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Perspectives on Minimally Invasive Approach to Resection of Colorectal Liver Metastases

Surgical resection is the most effective treatment approach in colorectal liver metastases. The im-proved survival in stage IV colorectal cancer is associated with a better diagnosis and evaluation, proper decision making, improved chemotherapy, and the adoption of parenchymal-sparing he-patic resections. Liver surgery was one of the last frontiers reached by minimally invasive surgery. Surgical techniques …

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An Uncommon Presentation of a Common Rectal Condition

We report a case of Solitary Rectal Ulcer Syndrome (SRUS) whose colonoscopy showed a rectal mass whose large pale appearance was uncommon and should be remembered as a presentation of SRUS. SRUS is a chronic, benign disorder commonly caused by consti-pation – clinical features can comprise of rectal bleeding, passage of mucous, rectal pain, tenesmus, …

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