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Hepcidin, Ferroportin and Hephaestin Levels in Inflammatory Bowel Disease; Are they Key Mediators of Anemia or Inflammation?

1. Abstract 1.1. Background: Anemia represents a significant problem in Inflammatory Bowel Disease (IBD) and diagnosis may be challenging due to inflammation. Hepcidin, ferroportin and hephaestin are novel Iron Regulatory Proteins (IRPs) involved in iron metabolism. This study aimed to identify the interactions of these proteins in IBD patients, guiding safe iron supplementation and effective …

Hepcidin, Ferroportin and Hephaestin Levels in Inflammatory Bowel Disease; Are they Key Mediators of Anemia or Inflammation? Read More »

Non Langerhans Cell Histiocytosis of the Rectum: Case Report and Review of the Literature

1. Abstract Histiocytosis is a condition resulting from the abnormal proliferation of dentritic cells of the mononuclear phagocytic system. Previously classified as Langerhans cell histiocytosis and non-Langerhans cell histiocytosis, and recently into 5 categories (L, C, R, M and H), it can be localized to an organ or have a systemic manifestation, affecting most commonly …

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Unusual ERCP Complication: Unwanted Course of Misdirected Bile

1. Abstract Biliary stent complications include stent migration, obstruction, fragmentation, bleeding, perforation, cholangitis, and post-ERCP pancreatitis. Stent migration is the most common adverse event (5-14%) and is associated with: dilated CBD >10mm, benign stricture etiology, concomitant sphincterotomy, stent duration >1 month, and type of stent placed (straight, 10Fr diameter, and length >9cm). Here, we present …

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A Rare Submandibular Space Foregut Duplication Cyst Mimicking a Lymphatic Malformation in a Child

1. Introduction A submandibular space (SMS) bronchopulmonary foregut cystic malformation (BPFCM) was mistaken for a lymphatic malformation (LM) and treated unsuccessfully with sclerotherapy. The purpose of this article is to describe the imaging features of this rare SMS BPFCM so that it can be differentiated from LMs and treated appropriately. We propose that BPFCM in …

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Giant Gists

1. Abstract Gastrointestinal stromal tumours(GIST) are not uncommon in clinical practice. However giant GIST are relatively rare and present as exophytic tumors. The treatment of these giant tumours are tailored according to the size, site and resectablity. When resectable, upfront surgery was done when the tumor profile precludes curative surgery, they are offered neoadjuvant Imatinib …

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High-Throughput Uplc-G2si-Hdms Based Discovery of the Effective Constituents of Yindan Pinggan Capsule Against Yang Huang Syndrome

1. Abstract 1.1. Background: Yindan Pinggan Capsule, a patent Chinese medicine, has a definite effect on Yang Huang syndrome. At present, the pharmacological activity and quality control of Yindan Pinggan Capsule have been studied, but its effective constituents on the treatment of Yang Huang syndrome are still unclear.

Castelman’s Disease Revealed by Cholestatic Jaundice: About a Case with Review of the Literature

1. Summary Castelman’s disease is a lymphoid proliferation characterized by a wide histological spectrum and a polymorphic clinical picture. It comes in two different forms, localized and multicentric. We report an observation of Castelman’s disease with a review of the literature in a 31-year-old patient who had consulted for cholestatic jaundice. It was a multicentric …

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