1. Abstract Lynch syndrome (LS) is a hereditary cancer syndrome caused by mutations in DNA mismatch repair (MMR) genes, leading to microsatellite instability (MSI) and increased cancer risk.
1. Abstract 1.1. Aims To evaluate the proportion/hospital-based prevalence of non-alcoholic fatty liver disease in diagnosed cases of polycystic ovarian syndrome and to evaluate and compare the various relevant biochemical parameters and their derangements in cases of PCOS with NAFLD and cases of PCOS without NAFLD.
Metabolic syndrome is highly associated with gastric cancer (GC) formation, although the reliability of individual indices for predicting intestinal metaplasia (IM) risk remains inconsistent.
Hemophagocytic Lymphohistiocytosis (HLH) is a rare but severe sys temic inflammatory syndrome, often classified under autoimmune conditions. It is characterised by the excessive activation and proliferation of cytotoxic T cells and histiocytes (macrophages), leading to widespread immune dysregulation. There are two types of HLH one is primary and the other is secondary.
1. Abstract Colovesical fistulas (CVFs) are significant complications arising from diverticulitis and colorectal cancer. These fistulas create abnormal connections between the colon and bladder, leading to symptoms like pneumaturia and fecaluria. Given the variability in symptoms,
1. Abstract 1.1. Background Ovarian cancer is one of the most common malignant tumors in the female reproductive system. CXC-motif chemokine ligand 10 (CXCL10) increases tumor infiltrating lymphocytes (TIL) infiltration and is closely related to ovarian cancer prognosis.
1. Abstract 1.1. Objective To explore the causal relationships between inflammatory factors and hepatic cancer and identify the role of serum metabolites as potential mediators.
1. Abstract 1.1. Background Two classical models have been proposed for the development of colorectal cancer (CRC) from colon epithelial cells.
1. Abstract A 50-year-old male who presents with worsening left upper quadrant pain for several months. The pain constant and tender over the left ribs, and worse when lying down.
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