Volume 10

Severe Hereditary Hemochromatosis Due to Heterozygous H63D Mutation: Unusual Presentation

1. Abstract 1.1. Introduction Diagnosis of hereditary hemochromatosis is based on molecular sequencing of the HFE gene in search for one of the three most frequent mutations: p.Cys282Tyr (C282Y); p.His63Asp (H63D) and pSer65Cys (S65C). Iron overload linked to the H63D mutation especially in the heterozygous state is not conventionally considered significant enough to cause the …

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Elevated Pre-chemotherapy Plasma High D-dimer Levels Affect Survival of Advanced Gastric Cancer: An analysis of propensity score

1. Abstract 1.1. Background: Gastric cancer is a prevalent malignancy of the digestive system. There are presently no efficacious indicators to evaluate its curative effect and prognosis. Increased plasma D-dimer was researched to have a really deep connection between neoplasm in advanced stages and bad Overall Survival (OS) for some malignancies in distinct rates.