Volume 4

Direct Acting Antivirals in Hepatitis C Virus Genotype 3 and Advanced Cirrhosis

Direct-Acting Antivirals (DAAs) have revolutionized the management of hepatitis C infection. However, genotype 3 cirrhosis is still difficult to treat. We report our experience in the management of geno- type 3 cirrhosis with DAA’s. We analysed 111 adult cirrhotics with genotype 3 infection of which 54 (48.6%) had Decom- pensated Cirrhosis (DC). Patients with Compensated

HO-1 as a Dynamic Sensor in the Livers of Chronic Cerebral Hypoperfusion Rats

Heme oxygenases, mainly including heme oxygenase-1(HO-1) and heme oxygenase-1(HO-2), play a key role in protecting from oxidative stress and inflammation associated with vascular disease. Little is known, however, about the roles of HO-1 and HO-2 in the livers of rats with chronic cerebral hypo perfusion. The study aims to evaluate the expression and roles of …

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Does Measured Aggression with Stereotactic Hypo Fractionated Radiotherapy and TACE Allow Liver Transplant in Patients with Hepatocellular Carcinoma with Portal Vein Tumour Thrombus – A Retrospective Study

Patients with liver confined HCC with PVTT and minimum 1000 cc volume of uninvolved cirrhotic liver underwent SHORT and TACE, former administered using Rapid Arc, dose 32-50Gy in 5-14 fractions. TACE was performed using gel foam slurry, Inj. C is platinum and PVA. Liver transplant was performed on radiological evidence of recanalization or conversion to …

Does Measured Aggression with Stereotactic Hypo Fractionated Radiotherapy and TACE Allow Liver Transplant in Patients with Hepatocellular Carcinoma with Portal Vein Tumour Thrombus – A Retrospective Study Read More »

An Unusual Cause of Abdominal Pain: Valentino’s Syndrome. A Case Report

Valentino’s syndrome is a rare entity that can mimic an acute appendicitis caused by the presence of a peptic ulcer which perforated appendicitis causes reactive drainage. Present a case 52- year-old male with clinical symptoms, radiographic and ultrasonographic data appendicitis, which is subjec- ted to laparotomy finding chemical periappendicitis attended by sliding FID turbid liquid …

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The Effect of Long-Term Human Albumin Administration on the Mortality of Adult Patients with De Compensated Liver Cirrhosis: A Meta-Analysis and Systematic Review

Liver disease accounts for approximately 2 million deaths per year worldwide, 1 million due to complications of cirrhosis. Mortality trends in cirrhosis have been increasing in the Phi- lippines; data from 1990 to 2010 showed that there has been an overall increase of mortality by 53.7%. One of the promising treatment options for patients with …

The Effect of Long-Term Human Albumin Administration on the Mortality of Adult Patients with De Compensated Liver Cirrhosis: A Meta-Analysis and Systematic Review Read More »