Case Report

Persistent Elevation of Serum Prothrombin Induced by Vitamin K Deficiency or Antagonist Despite Discontinuation of Warfarin Administration in Alcoholic Cirrhosis in The Absence of Hepatocellular Carcinoma: A Case Report

1. Abstract Whereas serum prothrombin induced vitamin K deficiency or antagonist II (PIVKA-II) is a di- agnostic and prognostic marker of hepatocellular carcinoma (HCC), the serum PIVKA-II level rarely increases in chronic liver diseases in the absence of HCC. Although warfarin administration induces marked elevation of PIVKA-II, warfarin discontinuation may lead to swift normalization of …

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Uncommon Cause of Gastrointestinal Bleeding

1. Introduction Gastric antral vascular ectasia is an uncommon cause of chronic gastrointestinal bleeding or iron deficiency anaemia [1]. The condition is associated with dilated small blood ves- sels in the antrum, or the last part of the stomach. It is also called watermelon stomach because streaky long red areas that are present in the …

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High-Dose Methotrexate, A Tried-and-True Treatment with Genomic Delicacies: A Case Report

1. Abstract The prediction of methotrexate (MTX) adverse events has been a challenge to the clinician; here we present a case of toxicity after the previous exposition with the development of hepatic, renal, and hematologic toxicity. The development of methotrexate toxicity has been previously analyzed in our institution, where a significant percentage of the patients …

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Prognostic Ability of Hematological Parameters and Inflammation Based Scores in Acute Pancreatitis

1. Abstract 1.1. Aims and Background: Appropriate triage is essential in the management of Acute Pancreatitis (AP). Even if AP initially stratified as mild or moderate, it may rapidly progress to severe form and even death may occur. Therefore, to find reliable prognostic and predictive markers in order to customize treatment strategies is really essential.

Alcoholic Chronic Pancreatitis or Intraductal Papillary Mucinous Neoplasm: What to Do?

1. Abstract Intraductal Papillary Mucinous Neoplasm (IPMN) is an intraductal mucin-producing neoplasm , with an increasing incidence. IPMNs may have clear malignant potential and exhibit a broad histo- logical spectrum ranging from adenoma to invasive carcinoma. In contrast to the ductal adenocar- cinoma, IPMNs have in general a better clinical prognosis.

Budesonide for Relapsed/Persistent Hepatitis in Two Patients with Hepatitis-Associated Aplastic Anemia Treated with Antithymocyte Globulin and Cyclosporine A Case Report

1. Abstract Flares of hepatitis with activity similar or even higher than peak activity during initial presentation are rare in patients with Hepatitis-Associated Aplastic Anemia (HAAA). We describe two children with HAAA in whom hepatitis with high transaminases activity persisted or relapsed after a course of antithymocyte globulin

An Uncommon Presentation of a Common Rectal Condition

We report a case of Solitary Rectal Ulcer Syndrome (SRUS) whose colonoscopy showed a rectal mass whose large pale appearance was uncommon and should be remembered as a presentation of SRUS. SRUS is a chronic, benign disorder commonly caused by consti-pation – clinical features can comprise of rectal bleeding, passage of mucous, rectal pain, tenesmus, …

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Giant Inflammatory Fibroid Polyp of Upper Esophagus: A Life -Threatening Rare Case

Inflammatory fibroid polyps IFPs of the esophagus are very uncommon. Giant IFPs are an extre-mely rare entity and the majority of them are located in the distal third of the esophagus. They are slowly growing and remain clinically “silent”. As the mass enlarges clinical symptoms appear with dysphagia, chest pain and food regurgitation being the …

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