Case Report

High-Dose Methotrexate, A Tried-and-True Treatment with Genomic Delicacies: A Case Report

1. Abstract The prediction of methotrexate (MTX) adverse events has been a challenge to the clinician; here we present a case of toxicity after the previous exposition with the development of hepatic, renal, and hematologic toxicity. The development of methotrexate toxicity has been previously analyzed in our institution, where a significant percentage of the patients …

High-Dose Methotrexate, A Tried-and-True Treatment with Genomic
Delicacies: A Case Report
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Prognostic Ability of Hematological Parameters and Inflammation Based Scores in Acute Pancreatitis

1. Abstract 1.1. Aims and Background: Appropriate triage is essential in the management of Acute Pancreatitis (AP). Even if AP initially stratified as mild or moderate, it may rapidly progress to severe form and even death may occur. Therefore, to find reliable prognostic and predictive markers in order to customize treatment strategies is really essential.

Alcoholic Chronic Pancreatitis or Intraductal Papillary Mucinous Neoplasm: What to Do?

1. Abstract Intraductal Papillary Mucinous Neoplasm (IPMN) is an intraductal mucin-producing neoplasm , with an increasing incidence. IPMNs may have clear malignant potential and exhibit a broad histo- logical spectrum ranging from adenoma to invasive carcinoma. In contrast to the ductal adenocar- cinoma, IPMNs have in general a better clinical prognosis.

Budesonide for Relapsed/Persistent Hepatitis in Two Patients with Hepatitis-Associated Aplastic Anemia Treated with Antithymocyte Globulin and Cyclosporine A Case Report

1. Abstract Flares of hepatitis with activity similar or even higher than peak activity during initial presentation are rare in patients with Hepatitis-Associated Aplastic Anemia (HAAA). We describe two children with HAAA in whom hepatitis with high transaminases activity persisted or relapsed after a course of antithymocyte globulin

An Uncommon Presentation of a Common Rectal Condition

We report a case of Solitary Rectal Ulcer Syndrome (SRUS) whose colonoscopy showed a rectal mass whose large pale appearance was uncommon and should be remembered as a presentation of SRUS. SRUS is a chronic, benign disorder commonly caused by consti-pation – clinical features can comprise of rectal bleeding, passage of mucous, rectal pain, tenesmus, …

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Giant Inflammatory Fibroid Polyp of Upper Esophagus: A Life -Threatening Rare Case

Inflammatory fibroid polyps IFPs of the esophagus are very uncommon. Giant IFPs are an extre-mely rare entity and the majority of them are located in the distal third of the esophagus. They are slowly growing and remain clinically “silent”. As the mass enlarges clinical symptoms appear with dysphagia, chest pain and food regurgitation being the …

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A Case of Severe Duodenitis in an Adult Patient with Hyper Ige Syndrome

We present the first case of severe duodenitis in the adult Japanese patient with hyper IgE syn- drome (HIES). A 41 years male patient, who has a treatment in the dermatology of our hospi- tal for severe dermatitis with hyper IgE syndrome, had a right frank pain with diarrhea for one week. Because he vomited …

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Hepatic Hydatid Diagnosed Before Operation but Mucinous Biliary Cystadenoma of Intrahepatic Bile Duct By Pathology after Operation: A Case Report

Intrahepatic biliary cystadenoma is a rare benign tumor of the liver, with less than 5% incidence. Although with the progress of imaging, the discovery of this disease species is more than before, but because this disease has no specific diagnostic means, the preoperative misdiagnosis rate is very high