Research Article

1. Abstract 1.1. Background: The current COVID-19 pandemic has put all health units in crisis. The easy transmissibility facilitated the fast spread to all countries, and Guatemala was not the exception. By May 2020 almost 229 thousand cases were reported, with 3.2% of case fatality. Among the principal mortality risks factors there are: advance age, …

Liver Injury as Mortality Risk Factor in Sars-Cov-2 Read More »

1. Abstract 1.1. Introduction: A few studies have investigated the occurrence of anti-ribosomal P antibody (Anti-P) in autoimmune hepatitis (AIH), based on the partial overlap of clinical and pathological features ofAIH and systemic lupus erythematosus (SLE), for which anti-P is a diagnostic biomarker. In face of the controversial results obtained, this study aimed to evaluate …

Anti-Ribosomal P (Anti-P) Antibodies in Autoimmune Hepatitis Patients Read More »

1. Abstract 1.1. Background: Prediction of liver cancer risk is beneficial to define high-risk population of liver cancer and guide clinical decisions. We aimed to review and critically appraise the quality of existing risk-prediction models for liver cancer.

1. Abstract 1.1. Background and Aims: Chemoradiotherapy represents one of the cornerstones of colorectal cancer management as not only it improves the local control but can also induce the histological resolution of the disease also known as the pathological complete response. The aim of this study is to identify predictive factors for cPR after chemoradiotherapy …

Weight Loss May be a Predictive Factor of Not Achieving Pathological Complete Response After Neoadjuvant Radiochemotherapy for Low Rectal Adenocarcinoma Read More »

1. Abstract 1.1. Background: Propofol is one of the most commonly used short-acting sedatives for painless gastrointestinal endoscopy. Local injection pain during injection was the most common adverse effect. Therefore, this study intended to use a randomized controlled study to observe the effect of pre-etomidate on propofol injection pain by using a small amount of …

Effect of Etomidate on the Prevention of Propofol Injection Pain in Painless Endoscopy Read More »

1. Abstract 1.1. Background: Extra-hepatic billiary obstruction is a common disorder seen in surgical practice, and it greatly affects the quality of life of patients afflicted with such disorder. In its severe form, it may be life threatening due to complications such as, hepatic encephalopathy, Hepato-renal syndrome, fulminant cholangitis and jaundice related coagulopathy. Obstructive Jaundice …

Palliative Cholecysto-Jejunostomy for Extra-Hepatic Billiary Obstruction Under Local Anaesthesia: A Rewarding Experience Read More »

1. Abstract 1.1. Background: Tripterygium Hypoglaucum Hutch (THH), extracts of a Chinese medicinal plant, shows immunosuppressive function and has been used in China for decades to treat autoimmune and inflammatory conditions. This retrospective study aimed to determine long-term efficacy of THH in treating patients with BD-associated uveitis. http://dx.doi.org/10.47829/JJGH.2021.61204

1. Abstract Hepatocellular Carcinoma (HCC) is a most common cause of cancer- related deaths globally. Traditional HCC treatments, including surgery, radiation therapy, and chemotherapy, could provide potential options; however, Sorafenib has been used for advanced HCC treatment. Unfortunately, most patients with advanced-stage HCC do not benefit from Sorafenib for its easy progression to resistance. Although …

Sorafenib-Induced Exosome Secretion Promotes Chemotherapy Resistance in Hepatoma Cell Line Read More »

1. Abstract 1.1. Background: Depression is a common comorbidity in chronic medical conditions including inflammatory bowel disease (IBD) and is a major determinant of health-related quality of life (HR-QOL). IBD patients often also experience chronic pain, and hence this population has significant opioid use. The aim of this study is to determine the prevalence of …

The Prevalence of Depression and Its Association with Prior Opioid Use Among Patients in an Outpatient IBD Program Read More »

1. Abstract 1.1. Introduction: Hepatitis B and hepatitis C virus (HBV and HCV) which have potential not only for causing both acute and chronic hepatitis but also are responsible for coinfection in HIV-infected patients.