Research Article

1. Abstract 1.1. Aims: The poor prognoses of hepatitis B virus (HBV) infection are correlated with hepatitis B e antigen (HBeAg). Current antiviral therapy does not directly interfere with HBeAg synthesis. HBeAg formation depends on proprotein convertase furin. To block HBeAg synthesis on purpose, galactosylated arginine-rich macromolecular furin inhibitors were developed and evaluated. DOI:http://dx.doi.org/10.47829/JJGH.2021.51002

1. Abstract 1.1. Introduction: Acute small bowel obstruction is a problem of modern surgery. It is not possible to study morphological and functional changes in the walls of the stomach in acute small bowel obstruction on clinical material, performing a biopsy in the dynamics of the development of the disease. Therefore, our work is experimental.

1. Abstract 1.1. Aim: The aim of this study is to make our contribution to the study of acute generalized peritonitis of typhus origin at the Kankan Regional Hospital. Typhoid perforation is defined as the opening of a hollow viscus in the abdominal cavity due to salmonella. 1.2. Methodology: We carried out a 6-month prospective …

Helicobacter Pylori Detection Among Sudanese Patients Diagnosed with Conlon Polyps and Colon Cancer Using Immunohistochemistry Technique Read More »

1. Abstract Coinfection with hepatitis B virus (HBV) and hepatitis C virus (HCV) is often associated with a higher risk of hepatocellular carcinoma (HCC). Here, we found that HBV X protein (HBx) and HCV core protein cooperate to inhibit p16 expression via DNA methylation in human hepatoma cells. For this purpose, they additively upregulated both …

Hepatitis B Virus X Protein and Hepatitis C Virus Core Protein Cooperate to Inhibit P16 Expression Via DNA Methylation Read More »

1. Abstract 1.1. Background: The aim of this study was to assess the quantitative composition of muscle and adipose tissue in type 2 diabetes mellitus (T2DM) patients on the basis of dual-energy X-ray absorptiometry for the diagnosis of obesity and sarcopenia. 1.2. Methods: Dual-energy X-ray absorptiometry was administered to 50 patients with T2DM. Evaluation of …

Assessment of Muscle and Fat Mass in Type 2 Diabetes Patients By Dual-Energy X-Ray Absorptiometry Read More »

1. Abstract 1.1. Background: Colorectal cancer is the most common tumor of the gastrointestinal tract, and it is the third leading cause of mortality throughout the world. 1.2. Objectives: An observational study of colorectal cancers. 1.3. Methods: The research was carried out in Abu Ghraib General hospital in the period from January 2019 to May …

Colon Versus Rectal Cancers among Surgical Approach: An Observational Study Read More »

1. Abstract 1.1 Background: This study aims to examine the prognostic factors of patients with MF ICC in order to improve the outcomes of ICC. 1.2. Methods: We carried out a retrospective analysis of consecutive patients with MF ICC treated at the Faculty of Hepato-Pancreato-Biliary Surgery of Chinese PLA General Hospital between January 2008 and …

Clinical Outcomes of Mass-Forming Intrahepatic Cholangiocarcinoma: A Case Series of 68 Patients Read More »

1. Abstract Sustained virological response 12 weeks after treatment (SVR12) with direct-acting antivirals (DAAs) is excellent in patients with hepatitis C but little has been published regarding decompensation and/or death during therapy. 1.1. Objectives: Objectives of this prospective, observational, multicenter study were to describe SVR12 in real life patients with advanced fibrosis/cirrhosis treated with DAAs …

Predictive Factors of Decompensation and Death in 670 Patients with Hepatitis C Treated with Direct-Acting Antivirals Read More »

1. Abstract 1.1. Introduction: Hepatitis is often a viral infection and Hepatitis B Virus (HBV) is reason in significant proportion of cases worldwide. Hepatitis B virus impact on liver can be of varying severity ranging from acute hepatitis to chronic hepatitis which can further lead to chronic liver disease, liver cirrhosis and hepatocellular carcinoma (HCC). …

Spectrum of Acute Hepatitis B at Tertiary Care Center of Northeren India Read More »

1. Abstract1.1. Background: Hepatocellular Carcinoma (HCC) is the 6th most common malignancy globally and it’s the most common tumor which originates primarily in the liver, the aim of this study is to find out the connection between increased serum nitric oxide (sNO) and its HCC predictive value in patients who received direct-acting antiviral agents (DAAs).1.2. …

Role of Serum Nitric Oxide in Prediction of Hepatocellular Carcinoma in Hepatitis CPatients Treated with Direct – Acting Antiviral Agents Read More »