Research Article

Tumor Microenvironment and Immune System in Early-Stage Breast Cancer: Distinct Pathways for Early Recurrence Following Mastectomy and Chemotherapy in Ductal and Lobular Types of the Disease

1. Abstract 1.1. Background: Intra-ductal cancer (IDC) is the most common type of breast cancer, with intra-lobular cancer (ILC) coming in second. Surgery is the primary treatment for early stage breast cancer. There are now irrefutable data demonstrating that the immune context of breast tumors can influence growth and metastasis. Adjuvant chemotherapy may be administered …

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Bioinformatics Analysis of Significant Host Immune Response Genes as Potential Biomarkers in COVID-19 Infection

1. Abstract 1.1. Introduction: The Corona virus disease 2019 (COVID-19) pandemic continues to spread across the world. Hereafter, require an urgent handling from health workers start from identification through clinical diagnosis of suspect COVID-19, sample collection and laboratory diagnosis of COVID-19 itself. We aimed to analyse the host immune response genes towards spikes protein as …

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Prevalence and Awareness of the HBsAg Status Among Pregnant Women in the Labour Room of the Ebolowa Regional Hospital

1. Abstract 1.1. Background: Most cases of chronic hepatitis B virus occur during child birth and early horizontal transmission in Sub-Saharan Africa, our study aimed at determining the level of awareness of the HBsAg status by pregnant women at the delivery room of the Ebolowa Regional Hospital and evaluate the prevalence of HBsAg among them.

Drug Repurposing for Inflammatory Bowel Disease Based On Relations Among Drugs, Diseases and Genes

1. Abstract Drug repurposing, which treats new and other diseases utilizing existing drugs, has turned into a much-valuable strategy. It can also be referred to as re-examination of existing drugs that have failed to indicate utility for new diseases. In this work, we mainly focused on finding inflammatory bowel disease (IBD) associated drugs based on …

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Acute Pancreatitis as First Manifestation of Severe Hypothyroidism: A Rare Case Report

1. Abstract We described the case of a 34-year-old Bangladeshi man with an unremarkable personal and family history who presented to the emergency department with severe upper abdominal pain of one day’s duration and with elevated serum amylase and lipase. Further work-up revealed a serum triglyceride level of 39.8 mmol/L and his thyroid function test …

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