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Impact Factor 4.452

Research Article

Rs1310191201(C>T) Polymorphism in 3‘UTR of BIRC5promote Carcinogenesis of Human Gastric Cancer by De-Regulation by Mir-330-5p in Chinese Population

Leave a Comment / Issue 9 Articles, Volume 4 / By

1. Abstract Previous reports have revealed that down-regulation of miR-330-5p expression can promote os- teosarcoma growth and invasion by targeting oncogene Baculoviral IAP repeat-containing pro- tein 5 (BIRC5). However, the function of the single nucleotide polymorphism (SNP) located in the 3’UTR of BIRC5 regulated by miR-330-5p has not been investigated in human Gastric Can- cer …

Rs1310191201(C>T) Polymorphism in 3‘UTR of BIRC5promote Carcinogenesis of Human Gastric Cancer by De-Regulation by Mir-330-5p in Chinese Population Read More »

Rapid SARS-Cov-2 Infection Spreading within a Family Cluster: The Importance of Gastro-Intestinal Symptoms

Leave a Comment / Issue 9 Articles, Volume 4 / By

1. Abstract 1.1. Background: In Phase-2 COVID-19 pandemic, timely control of new outbreaks is pivotal to avoid an epidemic rebound. A better knowledge of clinical disease profiles and the development of sensitive diagnostic flow charts will help to take more effectiveactions. 1.2. Patients and Methods: We studied an outbreak occurred in 3 families during a …

Rapid SARS-Cov-2 Infection Spreading within a Family Cluster: The Importance of Gastro-Intestinal Symptoms Read More »

Undertreatment of Hepatitis C Virus Infection in Elective Total Hip Arthroplasty

Leave a Comment / Volume 4 / By

Total Hip Arthroplasty (THA) in patients with hepatitis C virus (HCV) are known for poor outcomes increased risk of iatrogenic infection. New Direct Antiviral Agents (DAA) can now cure HCV infection. However, undertreatment is still common in patients undergoing THA. Our aim was to assess the prevalence of HCV infection and treatment rates inpatients with …

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Epidemiological Characteristics of De Novo Hepatitis B Infection in Liver Transplant Recipients – An Experience from a Tertiary Care Centre in Qatar

Leave a Comment / Issue 6 Articles, Volume 4 / By

Emergence of Hepatitis B Surface Antigen (HBsAg) in a patient with previously negative Hepatitis B Virus (HBV) serology post Orthotropic Liver Transplant (OTLX) is known as De-novo Hepatitis B (DNHB). To study the clinical profile and epidemiology of patients with DNHB in Qatar. This descriptive epidemiological study was done by retrospectively reviewing records of 159 …

Epidemiological Characteristics of De Novo Hepatitis B Infection in Liver Transplant Recipients – An Experience from a Tertiary Care Centre in Qatar Read More »

A Hepatocelluar Co-Culture System for the Investigation of Cellular-Based Mechanisms of Troglitazone-Induced Liver Injury

Leave a Comment / Issue 6 Articles, Volume 4 / By

Drug-induced liver injury (DILI) is a serious issue faced by the pharmaceutical industry, and often leads to drug withdrawal once patients experience drug-induced severe hepatic failure. We developed an in vitro assay system that enables to assess cellular damage and immune reaction responses that ultimately result in DILI using troglitazone as a model drug….

Prognostic Variables for Patients with T2N0M0 Esophageal Squamous Cell Carcinoma

Leave a Comment / Issue 5 Articles, Volume 4 / By

To explore the variables which could predict the prognosis and might be considered as staging factors in patients with T2N0M0 Esophageal Squamous Cell Carcinoma (ESCC).Records of 525 patients with pathologic T2N0M0 ESCC who underwent surgical resection were reviewed. The T2 category was further subdivided into T2a (circular muscle layers) and T2b (longitudinal muscle layers)….

Immunological Pathways in the Development of Postoperative Hyper- amylasemia and Postoperative Pancreatitis

Leave a Comment / Issue 5 Articles, Volume 4 / By

Postoperative pancreatitis complications can be separated into two main groups based on literature reviews and clinical trials. Some authors suggest that postoperative pancreatitis is a severe complication that should be treated conservatively and operatively if needed. Other authors defend an opposite opinion that only postoperative hyperamylasemia exists, which is a transitory condition with no risk …

Immunological Pathways in the Development of Postoperative Hyper- amylasemia and Postoperative Pancreatitis Read More »

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*2021 Journal unofficial Impact Factor was established by dividing the number of articles published in 2020 with the number of times they are cited in 2021 based on Google Scholar Citation Index database. If ‘X’ is the total number of articles published in 2020 and ‘Y’ is the number of times these articles were cited in indexed journals during 2021 then, journal impact factor = Y/X.

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