Research Article

Stressors have varied biological effects on gastrointestinal system which are increasingly recognized as enhanced gut permeability, dysbiosis and inflammation in the gut.Endotoxins, the metabolites released by harmful gut microbes are one of the stressors resulting

Surgical techniques applied to treat ano-rectal fistulas has proved variable results, depending on how complex the fistula is. Many publications report promising results regarding simple and complex trans-sphincter fistulas

With the avalanche of protein sequences generated in the post-genomic age, it is highly desired to develop AI tools for rapidly and effectively identifying the subcellular locations of uncharacterized proteins based on their sequences information

Several treatment strategies are available to treat achalasia. Although combined therapy has been used for several years, there are limited data on long-term outcomes. We aimed to determine its long-term efficacy in patients who were resistant or those with rapid relapse

After 3.65 (2-8) days of conservative treatment, the patients with no improvement in clinical and/or laboratory findings were considered to have complicated cholecystitis and underwent additional imaging procedures. In 20 patients, gallbladder perforation was observed, and a total of 22 catheters were placed

Non-steroidal anti-inflammatory drugs (NSAIDs) commonly used by people induces gastric injury. This study was designed to evaluate effects of ellagic acid as a natural compound on oxidative stress markers and immunohistochemical structure during experimental gastric damage

Cholesterol accumulation in growing tumor cells has recently been implicated in apoptosis evasion and drug resistance. Various reports have suggested the potential of statins (3-hydroxy-3-methylglutaryl-coenzyme Areductase inhibitors) as chemo preventive agents

Biliary leak is the most frequent complication in liver resections. The Second International Consensus Conference mentions a potentially higher incidence of bile leaks in Laparoscopic Liver Resection (LLR) that still needs to be evaluated

Minilaparoscopy instruments emerged as an alternative to conventional laparoscopic cholecystectomy trying to obtain a faster recuperation, however there are not randomized clinical trials conducted to establish its usefulness compared to conventional 3 ports laparoscopic cholecystectomy

Tumors of the small bowel representing 3% of all gastrointestinal malignancies (33% adenocarcinomas). We performed a retrospective study of the adenocarcinomas of the small bowel in 18 years