Research Article

Liver disease accounts for approximately 2 million deaths per year worldwide, 1 million due to complications of cirrhosis. Mortality trends in cirrhosis have been increasing in the Phi- lippines; data from 1990 to 2010 showed that there has been an overall increase of mortality by 53.7%. One of the promising treatment options for patients with …

The Effect of Long-Term Human Albumin Administration on the Mortality of Adult Patients with De Compensated Liver Cirrhosis: A Meta-Analysis and Systematic Review Read More »

Lipid raft, as scaffolding platform for signal transduction, plays important role in the liver re- generation. But the lipid raft protein expression pattern during liver regeneration has been not reported. In this study, lipid raft proteins from the liver of 72 h post partial hepatectomy and sham-operated group were identified by liquid chromatography-tandem mass spectrometry …

Mass Spectrometry Analysis Reveals Dynamic Changes of Protein Components in Lipid Rafts from Rat Liver after Partial Hepatectomy Read More »

The burden of therapy-related hand-foot skin reaction (HFSR) can reduce the benefit of treatment for patients. Evidence for the nursing management of sorafenib-related HFSR in nonclinical settings remains inadequate

To examine the effects of low dose Kelulut honey administration in dengue patients on the outcome of clinical, haematological and hemodynamic parameters. 47 serological positive dengue patients (age 33+11 year) were included in this doubleblinded randomized control trial. Twenty-four patients were given low dose of Kelulut honey (0.2 mg/kg/day) for 3 days, while 23 patients

At present, sedation in patients on mechanical ventilator remains the standard of care. However, many trials have shown that sedation was associated with worse outcomes (i.e. more days on mechanical ventilation and higher mortality rates). We explored the use of nonse- dation protocols as compared to conventional

Most hospital outpatients unaware of their Hepatitis B Virus (HBV) status could be seeking treatment for other different ailments in Kenya. To evaluate the HBV prevalence and the genetic diversity, the genetic analysis of the partial HBV S gene was conducted

Therapy for the Hepatitis C Virus (HCV) has undergone a revolution with the introduction of Direct-Acting Antivirals (DAA). DAAs achieve Sustained Virological Response (SVR) in 90-95% of treated patients, compared to 50-70% of those receiving dual pegylated interfere on and ribavir in therapy

Gastro-Oesophageal Varices (GOV) in the presence of liver fibrosis along with splenomegaly on USS abdomen are used as surrogate markers of portal hypertension for grading intestinal failure associated liver disease (IFALD). The severity of IFALD determines the type of intestinal transplant performed

Formaldehyde (FA) is a common environmental pollutant that can cause serious liver damage. The aim of this study is to investigate the effect of FA on cholesterol metabolism in human hepato cellular carcinoma cells (HepG2). After exposure to different concentrations of FA for 24 and 48 h, free cholesterol (FC) contents

Patients with plasma LDL values lower than 80 mg/dL were collected into the first, lower than 100 mg/dL into the second, lower than 130 mg/dL into the third, lower than 150 mg/dL into the fourth, and 150 mg/dL and higher into the fifth groups, respectively