Non-steroidal anti-inflammatory drugs (NSAIDs) commonly used by people induces gastric injury. This study was designed to evaluate effects of ellagic acid as a natural compound on oxidative stress markers and immunohistochemical structure during experimental gastric damage
Cholesterol accumulation in growing tumor cells has recently been implicated in apoptosis evasion and drug resistance. Various reports have suggested the potential of statins (3-hydroxy-3-methylglutaryl-coenzyme Areductase inhibitors) as chemo preventive agents
Biliary leak is the most frequent complication in liver resections. The Second International Consensus Conference mentions a potentially higher incidence of bile leaks in Laparoscopic Liver Resection (LLR) that still needs to be evaluated
Minilaparoscopy instruments emerged as an alternative to conventional laparoscopic cholecystectomy trying to obtain a faster recuperation, however there are not randomized clinical trials conducted to establish its usefulness compared to conventional 3 ports laparoscopic cholecystectomy
Tumors of the small bowel representing 3% of all gastrointestinal malignancies (33% adenocarcinomas). We performed a retrospective study of the adenocarcinomas of the small bowel in 18 years
The small bowel is an unusual site for malignancies. In patients with Crohn’s Disease there is an enlarged relative risk of small bowel adenocarcinoma likened to the general population. Signet ring cell carcinoma is a rare type of adenocarcinoma that predominantly affects the stomach
Although the international guidelines recommend the CDH1 germline mutations screening in patients at risk of carrying pathogenic mutations, few data exist about the compliance to systematic screening programs carried out in surgical centres
Imaging biomarkers are needed to assess modifications in pancreatic adenocarcinoma (PA) induced by stroma-targeted therapies. The study investigates correlations between quantitative diffusion parameters obtained in vivo and ex vivo with a tumour volumetric approach and quantitative pathologic findings including fibrosis, vascular and total nuclear densities in PA
There are quite more than dozens studies in world literature concerning the problems of the quality of life of patients with colorectal cancer in a wide variety of clinical and socio-individual aspects. It is significantly difficult any specific screening and stratified grouping of similar problems in patients with locally advanced cancerboth of the colon and …
To assess the benefits of performing endoluminal forceps biopsy during initial drainage compared to postponed biopsy using two patient management scenarios. Since 2006, 101 consecutive patients with malignant biliary stenosis due to cholangiocellular carcinoma have been followed up. All patients underwent a percutaneous biliary drainage (PBD) procedure and endoluminal forceps biopsy to obtain histological verification …
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