Research Article

1. Abstract 1.1. Background: Extracellular vesicle derived-DNA (EV DNA) have emerged as attractive diagnostic biomarkers in diseases diagnosis, while its role in metastatic colorectal cancer (mCRC) is unknown. This study aimed to explore the role of EV DNA in monitoring of gene mutations related to drug resistance during therapy with the anti-EGFR antibody cetuximab.

1. Abstract 1.1. Background: Bariatric surgery is considered a life-saving intervention for treating morbid obesity. The overall reduction in caloric intake accompanied by reduced intake of proteins and several key nutrients, such as iron and vitamin B12 can severely affect various hematological markers, including hemoglobin, hematocrit, and RBC count. This study aimed to investigate the …

Hematological Changes post Bariatric Surgery in Saudi Arabia; Single Tertiary Care Center Experience Read More »

1. Abstract 1.1. Background: Advanced endoscopy, namely endoscopic retrograde cholangiopancreatography (ERCP), has an integral role in the diagnosis and management of patients with Inflammatory Bowel Disease (IBD). ERCP is frequently performed in this population to diagnose Primary Sclerosing Cholangitis (PSC) or to manage strictures. This study aims to evaluate ERCP-related AEs in IBD patients using …

Measure Twice, Cut Once: Appraising The Safety of ERCP in IBD Read More »

1. Abstract 1.1. Objective: Nonalcoholic Fatty Liver Disease (NAFLD) is the most important cause of hepatic steatosis and hypertransaminasemia in western countries. The objective was to evaluate the prevalence of NAFLD among a population of 261025 people in the East Valladolid public healthcare area in Spain.

1. Abstract 1.1. Introduction: Anastomotic leaks and fistulas as well as perforations do lead to increased morbidity and mortality. Several interventional endoscopic techniques such as stents, clips, endoscopic suturing and endoscopic vacuum therapy, can help in reducing an unfavorable outcome of these patients, using a differentiated management of leakages. An important feature of these therapeutic …

Potential of Absorption, Capillary Effect and Sponge-Effect in Endoscopic-Assisted Therapy for Leaks and Fistulas Read More »

1. Abstract 1.1. Objectives This study aims to investigate changes in esophageal function in patients with gastroesophageal reflux-induced chronic cough (GERC) evaluated by high-resolution esophageal manometry (HRM).

1. Abstract 1.1. Background and study aim: The study aimed to explore the effect of Qihuang decoction on gastrointestinal motility and secretory function after gastrectomy.

1. Abstract 1.1. Background: Anorectal abscesses have become a common surgical problem, approximately one third of them also have anal fistulae; management can be conservative with antibiotics or needle aspiration and simple drainage with local anesthesia, considering them sufficient to remit the acute condition of this pathology. However, this line of treatment has been associated …

Primary Fistulotomy and Surgical Drainage Abscess is Associated with Low Fistula Recurrence Rate Read More »

1. Abstract 1.1. Objective: To analyze prospectively a series of 300 cases of hemorrhoidal disease managed with transanal hemorrhoidal dearterialization guided by Doppler ultrasound (THD) DOI:http://dx.doi.org/10.47829/JJGH.2022.8501

1. Abstract 1.1. Background: Model for End-stage Liver Disease (MELD) has been considered as a poor prognostic indicator for patients with liver failure in most previous studies, however, some studies suggest that MELD is not ideal in clinical application. Therefore, new studies on MELD and poor outcomes in patients with liver failure are still necessary. …

In-Hospital Mortality of Patients with Liver Failure: A Propensity Score Matched Cohort Study Read More »