1. Introduction Based on test data, we have experienced cases in which atopic dermatitis patients have a high multi-antigen positive rate, which is not seen in patients with allergic diseases such as bronchial asthma and allergic rhinitis. In addition, we often encounter patients with atopic dermatitis who have exorbitant IgE levels. In addition, it is …
1. Abstract 1.1. Introduction: One of the roles of the general practitioner is to spot, treat and verify the eradication of the H. pylori infection. The aim of this study was to carry out an inventory of the management of the H. pylori infection by the general practitioners from Picardie.
1. Abstract 1.1. Introduction: Anastomotic leaks after colorectal surgery is associated with serious morbidity and early diagnosis is critical. C-reactive protein (CRP) on postoperative day (POD) 3 to 5 has been described as a good predictor of anastomotic leak. Therefore, this study aims to review if CRP level of greater than 150mg/l is a reliable …
1. Abstract 1.1. Objective: To evaluate pepsinogen 1 (Pg 1) level in serum and pepsinogen 1 to pepsinogen 2 ration (Pg 1/2) in patients with AG and GC and compare them to gold standard endoscopic examination in those patients, to detect the sensitivity and specify of these markers to evaluate their value as a future …
1. Abstract Recurrent oral ulcers (OU) are a common manifestation in infancy affecting up 40% of children. The first step necessary for the diagnosis is the search for associated systemic symptoms. Recurrent aphthous stomatitis (RAS) is the most common diagnosis in patients with isolated OU, being a diagnosis of exclusion. Among patients with associated symptoms, …
1. Abstract Globally, metabolic associated fatty liver disease (MAFLD) is the leading cause of liver disease and the most common cause for liver transplantation. Type 2 Diabetes mellitus (T2DM) is major risk factor for development of MAFLD with Indian prevalence of 56.5% T2DM patients suffering from MAFLD. MAFLD and T2DM are pathophysiological linked with IR, …
1. Abstract Immunogenic Cell Death (ICD) plays an important role in the treatment of colorectal cancer, and the relevant molecular mechanisms of its role in colorectal cancer are closely related to a variety of Damage-Associated Molecular Patterns (DAMPs), such as calreticulin (CRT), Heat Shock Protein (HSP), Adenosine Triphosphate (ATP), high mobility group protein B1 (HMGB1) …
Expression Mechanism of Immunogenic Cell Death-Related Molecules in Colorectal Cancer Read More »
1. Abstract Colorectal cancer (CRC) is a substantial public health challenge across the globe. Transforming growth factor-β (TGF-β) is a critical pathway in CRC that regulate numerous cellular processes, including immune-suppression, growth inhibition, cell migration, invasion, epithelial-to-mesenchymal transition and extracellular matrix remodeling. Metastasis is the major cause of death in patients with colorectal cancer. TGF-β …
Role of TGF-Β in Colorectal Cancer: Mechanisms, Diagnosis and Therapies Read More »
1. Abstract Thrombocytopenia is a common sequela of chemotherapy treatment of many non-hematologic malignancies. Severe thrombocytopenia may necessitate halting chemotherapy or lead to hemorrhagic complications that impact patient morbidity and mortality. Partial Splenic Embolization (PSE) has been shown to be effective at improving platelet counts in appropriately selected patients and allowing for the resumption of …
Partial Splenic Embolization for the Treatment of Thrombocytopenia in Cancer Patients Read More »
1. Abstract The diagnosis of Cancer of Unknown Primary is difficult even in the present era of modern medicine. The incidence is closed to 2-5% of all epithelial cancers. There is no concrete explanation behind the development of these cancers, however, recent studies suggested the role of chromosomal abnormalities and neoangiogenesis in the development. Overall, …
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