Fecal Microbiota Transplantation for Liver Disease
1. Abstract The human gut contains a large and complex community of microorganisms that play an important role in maintaining the normal physiological activities of the host.
Review Article
Prevention of Hepatitis-B Reactivation During Immunosuppressive Therapy, Chemotherapy, Treatment with Biological Agents and After Organ Transplantation
1. Introduction Hepatitis B virus (HBV) is a major health problem worldwide. It is estimated that one in 3 persons have been exposed to HBV and around 400 million have chronic HBV.[1, 2] In Saudi Arabia the prevalence of HBV markers before implementation of HBV immunization (1990) was reported to be 50% for a single …
Treatment of Wilson Disease in Japan: An Insurance Claims Database Study
1. Abstract 1.1. Background & Aims: Wilson disease (WD) is a rare hereditary disease of copper metabolism. For such rare diseases, analysis of health insurance claims databases allows data collection from large numbers of patients. The objective of this study was to evaluate the characteristics and treatment of patients with WD in Japan using the …
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Atopic Dermatitis is a Multi-Organ Disorder Disease Involving Not Only the Skin but also the Intestinal Tract
1. Introduction Based on test data, we have experienced cases in which atopic dermatitis patients have a high multi-antigen positive rate, which is not seen in patients with allergic diseases such as bronchial asthma and allergic rhinitis. In addition, we often encounter patients with atopic dermatitis who have exorbitant IgE levels. In addition, it is …
Screening, Diagnosis and Treatment of Patients Infected with Hylicobacter Pylori by General Practitioners in Picardie: Results of a Cross-Sectional Observational Study
1. Abstract 1.1. Introduction: One of the roles of the general practitioner is to spot, treat and verify the eradication of the H. pylori infection. The aim of this study was to carry out an inventory of the management of the H. pylori infection by the general practitioners from Picardie.
Role of C-Reactive Protein (CRP) as a Predictive Marker of Anastomotic Leak in Colorectal Surgery: Is it Still Reliable?
1. Abstract 1.1. Introduction: Anastomotic leaks after colorectal surgery is associated with serious morbidity and early diagnosis is critical. C-reactive protein (CRP) on postoperative day (POD) 3 to 5 has been described as a good predictor of anastomotic leak. Therefore, this study aims to review if CRP level of greater than 150mg/l is a reliable …
Study of Serum Pepsinogen 1 and Pesinogen1 to Pepsinogen 2 Ratio Level as a Screening for Atrophic Gastritis and Gastric Cancer
1. Abstract 1.1. Objective: To evaluate pepsinogen 1 (Pg 1) level in serum and pepsinogen 1 to pepsinogen 2 ration (Pg 1/2) in patients with AG and GC and compare them to gold standard endoscopic examination in those patients, to detect the sensitivity and specify of these markers to evaluate their value as a future …
The Diagnostic Challenge of Recurrent Oral Aphtosis in Children: One Symptom, Many Diagnoses
1. Abstract Recurrent oral ulcers (OU) are a common manifestation in infancy affecting up 40% of children. The first step necessary for the diagnosis is the search for associated systemic symptoms. Recurrent aphthous stomatitis (RAS) is the most common diagnosis in patients with isolated OU, being a diagnosis of exclusion. Among patients with associated symptoms, …
Can combination of SGLT2 inhibitors and DPP-4 inhibitors be combination of choice for T2DM associated MAFLD?
1. Abstract Globally, metabolic associated fatty liver disease (MAFLD) is the leading cause of liver disease and the most common cause for liver transplantation. Type 2 Diabetes mellitus (T2DM) is major risk factor for development of MAFLD with Indian prevalence of 56.5% T2DM patients suffering from MAFLD. MAFLD and T2DM are pathophysiological linked with IR, …
Expression Mechanism of Immunogenic Cell Death-Related Molecules in Colorectal Cancer
1. Abstract Immunogenic Cell Death (ICD) plays an important role in the treatment of colorectal cancer, and the relevant molecular mechanisms of its role in colorectal cancer are closely related to a variety of Damage-Associated Molecular Patterns (DAMPs), such as calreticulin (CRT), Heat Shock Protein (HSP), Adenosine Triphosphate (ATP), high mobility group protein B1 (HMGB1) …
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