Review Article

Bcl-2 and SIRT3 Affect Tumor Cell Viability by Integrating Metabolism and Apoptosis

While apoptotic tolerance caused by B cell lymphoma 2 (Bcl-2) over expression is one of the important underlying mechanisms of the decreased apoptotic sensitivity of tumor cells, only tar- geting Bcl-2 as an anticancer therapy has shown limited clinical benefit, which may be related to the non-apoptotic protective effects of Bcl-2, such as its roles …

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Metamorphosis (Transfiguration) of Spontaneous Bacterial Peritonitis

Nowadays between 30% and 50% of patients with liver cirrhosis die due to bacterial infections [1, 2]. Spontaneous Bacterial Peritonitis (SBP) is a big complication of the severe complication “ascites” in liver cirrhosis [3-5]. SBP is the main cause of death in patients with cirrhosis [2, 6]. SBP does not arisefrom intraabdominal source which requiressurgery …

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The Chronic Hepatitis B Treatment Virologic Response to HAART among HBV/ HIV Co-Infected Patients Who Failed Lamivudine Containing Regimens

All HIV/HBV co-infected patients in Serbia have been treated with HAART containing an anti- HBV drug, irrespective of CD4 cell count and HBV disease status in order to prevent more active liver disease. Like in many developing countries, lamivudine containing HAART was used in all HBV/HIV co-infected individuals