Review Article

Bcl-2 and SIRT3 Affect Tumor Cell Viability by Integrating Metabolism and Apoptosis

While apoptotic tolerance caused by B cell lymphoma 2 (Bcl-2) over expression is one of the important underlying mechanisms of the decreased apoptotic sensitivity of tumor cells, only tar- geting Bcl-2 as an anticancer therapy has shown limited clinical benefit, which may be related to the non-apoptotic protective effects of Bcl-2, such as its roles …

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Metamorphosis (Transfiguration) of Spontaneous Bacterial Peritonitis

Nowadays between 30% and 50% of patients with liver cirrhosis die due to bacterial infections [1, 2]. Spontaneous Bacterial Peritonitis (SBP) is a big complication of the severe complication “ascites” in liver cirrhosis [3-5]. SBP is the main cause of death in patients with cirrhosis [2, 6]. SBP does not arisefrom intraabdominal source which requiressurgery …

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