Volume 4

Alcoholic Chronic Pancreatitis or Intraductal Papillary Mucinous Neoplasm: What to Do?

1. Abstract Intraductal Papillary Mucinous Neoplasm (IPMN) is an intraductal mucin-producing neoplasm , with an increasing incidence. IPMNs may have clear malignant potential and exhibit a broad histo- logical spectrum ranging from adenoma to invasive carcinoma. In contrast to the ductal adenocar- cinoma, IPMNs have in general a better clinical prognosis.

Laparoscopic Cholecystectomyrisk Factors, Intra and Postoperative Complications in Al-Zahrawi Hospital, Amara, Misan, Iraq

1. Abstract 1.1. Background: Cholecystectomy relieves pain, treats infections and in most instances prevents the re-occurrence of the disorder. However, some complications may happen which include bile leak, bile duct injury, bleeding, peritonitis, liver and intestine injuries, raised scare at the operation site, anesthesia complications and possible death.

Budesonide for Relapsed/Persistent Hepatitis in Two Patients with Hepatitis-Associated Aplastic Anemia Treated with Antithymocyte Globulin and Cyclosporine A Case Report

1. Abstract Flares of hepatitis with activity similar or even higher than peak activity during initial presentation are rare in patients with Hepatitis-Associated Aplastic Anemia (HAAA). We describe two children with HAAA in whom hepatitis with high transaminases activity persisted or relapsed after a course of antithymocyte globulin

Administration of Selective Serotonin Reuptake Inhibitors and Risk of Pyogenic Liver Abscess in a Case-Control Study

1. Abstract 1.1. Background/Objective: Little research is available between Selective Serotonin Reuptake Inhibitors (SSRIs) use and incidence of Pyogenic Liver Abscess (PLA). The objective of the study was to determine whether SSRIs use is associated with PLA. 1.2. Methods: There were 1749 subjects, who had the first episode of PLA between 2000 and 2013, were …

Administration of Selective Serotonin Reuptake Inhibitors and Risk of
Pyogenic Liver Abscess in a Case-Control Study
Read More »

Rs1310191201(C>T) Polymorphism in 3‘UTR of BIRC5promote Carcinogenesis of Human Gastric Cancer by De-Regulation by Mir-330-5p in Chinese Population

1. Abstract Previous reports have revealed that down-regulation of miR-330-5p expression can promote os- teosarcoma growth and invasion by targeting oncogene Baculoviral IAP repeat-containing pro- tein 5 (BIRC5). However, the function of the single nucleotide polymorphism (SNP) located in the 3Â’UTR of BIRC5 regulated by miR-330-5p has not been investigated in human Gastric Can- cer …

Rs1310191201(C>T) Polymorphism in 3‘UTR of BIRC5promote Carcinogenesis of Human Gastric Cancer by De-Regulation by Mir-330-5p in Chinese Population Read More »

Rapid SARS-Cov-2 Infection Spreading within a Family Cluster: The Importance of Gastro-Intestinal Symptoms

1. Abstract 1.1. Background: In Phase-2 COVID-19 pandemic, timely control of new outbreaks is pivotal to avoid an epidemic rebound. A better knowledge of clinical disease profiles and the development of sensitive diagnostic flow charts will help to take more effectiveactions. 1.2. Patients and Methods: We studied an outbreak occurred in 3 families during a …

Rapid SARS-Cov-2 Infection Spreading within a Family Cluster: The Importance of Gastro-Intestinal Symptoms Read More »

Bcl-2 and SIRT3 Affect Tumor Cell Viability by Integrating Metabolism and Apoptosis

While apoptotic tolerance caused by B cell lymphoma 2 (Bcl-2) over expression is one of the important underlying mechanisms of the decreased apoptotic sensitivity of tumor cells, only tar- geting Bcl-2 as an anticancer therapy has shown limited clinical benefit, which may be related to the non-apoptotic protective effects of Bcl-2, such as its roles …

Bcl-2 and SIRT3 Affect Tumor Cell Viability by Integrating Metabolism and Apoptosis Read More »

Undertreatment of Hepatitis C Virus Infection in Elective Total Hip Arthroplasty

Total Hip Arthroplasty (THA) in patients with hepatitis C virus (HCV) are known for poor outcomes increased risk of iatrogenic infection. New Direct Antiviral Agents (DAA) can now cure HCV infection. However, undertreatment is still common in patients undergoing THA. Our aim was to assess the prevalence of HCV infection and treatment rates inpatients with …

Undertreatment of Hepatitis C Virus Infection in Elective Total Hip Arthroplasty Read More »