Issue 1 Articles

Effects of Different Capsule Types for Oral Application of Active Substances – Investigations with Organ-Specific Cells

1. Abstract 1.1. Background: A capsule is a solid dosage form that delivers a defined dose of an active ingredient. Most capsules are made for oral application by mouth with subsequent swallowing. Capsule materials for the shell are not only of importance for the release of active ingredients, but should also be without any impact …

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Liver Injury as Mortality Risk Factor in Sars-Cov-2

1. Abstract 1.1. Background: The current COVID-19 pandemic has put all health units in crisis. The easy transmissibility facilitated the fast spread to all countries, and Guatemala was not the exception. By May 2020 almost 229 thousand cases were reported, with 3.2% of case fatality. Among the principal mortality risks factors there are: advance age, …

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Trousseau’s Syndrome in a Patient with Advanced Pancreatic Cancer: A Case Report

1. Abstract 1.1. Background Trousseau’s syndrome was first described in 1865, by Armand Trousseau, as migratory superficial thrombophlebitis forewarning of visceral malignancy [1]. This syndrome is well known, partly because Armand Trousseau not only described it , but also diagnosed the syndrome on himself two years later secondary to gastric cancer [2]. http://dx.doi.org/10.47829/JJGH.2021.61502

The Image Of Gross Type C Esophageal Atresia Concomitant With Duodenal Atresia

1. Abstract Esophageal atresia with or without tracheoesophageal fistula is an extremely rare congenital anomaly. It is frequently associated with other malformations. However, gastrointestinal anomalies are encountered with esophageal atresia, concomitant with duodenal atresia is rare. The image shows a blind pouch with the radio-opaque agent showing esophageal atresia, and a double bubble sign showing …

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An Unexpected Complication of Cholecystitis

1. Clinical Image A 54-year-old woman with history of cholangiocarcinoma with treatment consisting in endoscopic biliary stents implantation and six month of chemotherapy, was referred to the emergency department for fever and shivers started 7 days earlier. On physical examination, she presented a significant pain in the abdominal right upper quadrant, tachycardia, and hypotension. Blood …

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Anti-Ribosomal P (Anti-P) Antibodies in Autoimmune Hepatitis Patients

1. Abstract 1.1. Introduction: A few studies have investigated the occurrence of anti-ribosomal P antibody (Anti-P) in autoimmune hepatitis (AIH), based on the partial overlap of clinical and pathological features ofAIH and systemic lupus erythematosus (SLE), for which anti-P is a diagnostic biomarker. In face of the controversial results obtained, this study aimed to evaluate …

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