Issue 1 Articles

Transjugular Intrahepatic Portosystemic Shunt Infection: A Case Study of Bacteraemia caused by Escherichia Coli

1. Abstract 1.1. Background It is widely believed that liver transplantation is the only way to cure hepatic cirrhosis. However, due to limited funds and liver donors, liver transplantation is seldom performed in Asia, especially in China. For patients who have experienced oesophageal and gastric varices bleeding and waiting for a liver transplant, transjugular intrahepatic …

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Importance of Ibd Biopsy Protocol In Clinical Practice: Analyses Comparing Two British Patients’ Cohorts

1. Abstract 1.1. Background & Aims: The correlation of histological features with clinical and endoscopic data is one of the crucial steps in the accurate diagnosis of inflammatory bowel disease (IBD). This study compares the diagnostic and clinical outcomes of two cohorts of patients undergoing colonoscopy before and after the introduction of a formal biopsy …

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Diagnosis At First Sight: Fish-Eye Ampulla

1. Clinical Image A 62-year-old woman is presented with nausea, vomiting, abdominal pain, fever, and pale color of defecation for one week. She denied other gastrointestinal symptoms. Physical examination was unremarkable. Laboratory tests showed the following abnormal tests: SGPT: 131 U/L, SGOT: 56 U/L, ALP: 575 U/L, GGT: 911 U/L, Total bilirubin: 10,4 mg/dL, direct …

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Efficacy of Pemafibrate Against Nonalcoholic Fatty Liver Disease: A Prospective Cohort Study

1. Abstract 1.1. Background: Nonalcoholic fatty liver disease (NAFLD), one of the most common causes of chronic liver diseases, is characterized by chronic liver inflammation and fibrosis, which consequently promote cirrhosis and liver cancer. Pemafibrate, a selective PPARα modulator is a new lipid-lowering drug that provides better hypertriglyceridemia control compared to greater other fibrates without …

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Treatment Protocol of the Most Common Anorectal Pathologies with Association between Micronized Purified Flavonoid Fraction and Sucralfate for Local Application

1. Summary (Aim) The author proposes to test the effectiveness of the combined action of 1- Micronized Purified Flavonoid Fraction – MPFF associated with topical action “barrier effect” of 2 – Sucralfate (as SOS – Sucralfate Ointment with Soothing Herbs) for some of the most common anal pathological situations with two main objectives:   DOI:http://dx.doi.org/10.47829/JJGH.2021.8202

Immunological Reason for Mild Affection of Children to COVID-19, A Key Factor for Novel Solution of Vaccination and Medications

1. Abstract Coronaviruses are important human and animal pathogens. We will show that probably antibodies don’t have essential role in immunity against COVID-19 in long term, but a type of white globules named T cells may have critical role in immunity against COVID-19. T cells have long time memory to remain in blood.

Anesthetic Management for Patients With Pheochromocytoma : Series of Three Cases

1. Abstract 1.1. Background. This study describes a case series that addresses the complex anesthetic management of adrenalectomy for patients with pheochromocytoma. It is a rare tumor, originating in the chromaffin cells of the adrenal medulla and a catecholamine-secreting agent, whose most common triad of symptoms is headache, sweating and tachycardia. DOI:http://dx.doi.org/10.47829/JJGH.2021.8201

Microrna-145 Inhibits EMT and Fibrosarcoma Cell Proliferation, Migration and Invasion by Targeting HMGA2

1. Abstract 1.1 Aim: Fibrosarcoma is a rare malignant tumor of subcutaneous tissue characterized by slow infiltrative growth and a high rate of local recurrence. The participation of microRNAs (miRNAs/miRs) in the pathogenesis of human diseases and the vital role of miR-145 in different types of cancer. However, the role of miR-145 in fibrosarcoma remains …

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Primary Biliary Cholangitis and Type 1 Diabetes in A Male Patient: A Case Report

1. Abstract Primary Biliary Cholangitis (PBC) isa cholestatic disease of autoimmune origin characterized by the destruction of small to medium size intrahepatic bile ducts due to lymphocytic infiltration. The diagnosis is made by the presence of Anti-Mitochondrial Antibodies (AMAs) specific for the disease. PBC typically affects middle-aged women and is often associated with other autoimmune …

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