Research Article

Direct-Acting Antivirals (DAAs) have revolutionized the management of hepatitis C infection. However, genotype 3 cirrhosis is still difficult to treat. We report our experience in the management of geno- type 3 cirrhosis with DAA’s. We analysed 111 adult cirrhotics with genotype 3 infection of which 54 (48.6%) had Decom- pensated Cirrhosis (DC). Patients with Compensated

Recent studies have found that elevated uric acid in intestine during an inflammatory response could exacerbate intestinal disease. The aim of this study was to investigate the association of serum uric acid level with Chinese ulcerative colitis

Heme oxygenases, mainly including heme oxygenase-1(HO-1) and heme oxygenase-1(HO-2), play a key role in protecting from oxidative stress and inflammation associated with vascular disease. Little is known, however, about the roles of HO-1 and HO-2 in the livers of rats with chronic cerebral hypo perfusion. The study aims to evaluate the expression and roles of …

HO-1 as a Dynamic Sensor in the Livers of Chronic Cerebral Hypoperfusion Rats Read More »

Patients with liver confined HCC with PVTT and minimum 1000 cc volume of uninvolved cirrhotic liver underwent SHORT and TACE, former administered using Rapid Arc, dose 32-50Gy in 5-14 fractions. TACE was performed using gel foam slurry, Inj. C is platinum and PVA. Liver transplant was performed on radiological evidence of recanalization or conversion to …

Does Measured Aggression with Stereotactic Hypo Fractionated Radiotherapy and TACE Allow Liver Transplant in Patients with Hepatocellular Carcinoma with Portal Vein Tumour Thrombus – A Retrospective Study Read More »

Liver disease accounts for approximately 2 million deaths per year worldwide, 1 million due to complications of cirrhosis. Mortality trends in cirrhosis have been increasing in the Phi- lippines; data from 1990 to 2010 showed that there has been an overall increase of mortality by 53.7%. One of the promising treatment options for patients with …

The Effect of Long-Term Human Albumin Administration on the Mortality of Adult Patients with De Compensated Liver Cirrhosis: A Meta-Analysis and Systematic Review Read More »

Lipid raft, as scaffolding platform for signal transduction, plays important role in the liver re- generation. But the lipid raft protein expression pattern during liver regeneration has been not reported. In this study, lipid raft proteins from the liver of 72 h post partial hepatectomy and sham-operated group were identified by liquid chromatography-tandem mass spectrometry …

Mass Spectrometry Analysis Reveals Dynamic Changes of Protein Components in Lipid Rafts from Rat Liver after Partial Hepatectomy Read More »

The burden of therapy-related hand-foot skin reaction (HFSR) can reduce the benefit of treatment for patients. Evidence for the nursing management of sorafenib-related HFSR in nonclinical settings remains inadequate

To examine the effects of low dose Kelulut honey administration in dengue patients on the outcome of clinical, haematological and hemodynamic parameters. 47 serological positive dengue patients (age 33+11 year) were included in this doubleblinded randomized control trial. Twenty-four patients were given low dose of Kelulut honey (0.2 mg/kg/day) for 3 days, while 23 patients

At present, sedation in patients on mechanical ventilator remains the standard of care. However, many trials have shown that sedation was associated with worse outcomes (i.e. more days on mechanical ventilation and higher mortality rates). We explored the use of nonse- dation protocols as compared to conventional

Most hospital outpatients unaware of their Hepatitis B Virus (HBV) status could be seeking treatment for other different ailments in Kenya. To evaluate the HBV prevalence and the genetic diversity, the genetic analysis of the partial HBV S gene was conducted