Research Article

Prevalence of Nocturnal Leg Cramps in Patients with Liver Disease is Higher than with Other Chronic Disease

A nocturnal leg cramps (NLC) is caused by a continuous, involuntary, painful, and localized contraction of a muscle or simply some muscle bundles.NLC is associated with a reduced quality of sleep and a subsequent lower health related quality of life. The purpose of our study is to clarify both prevalence and characteristics of NLC in …

Prevalence of Nocturnal Leg Cramps in Patients with Liver Disease is Higher than with Other Chronic Disease Read More »

The Relationship between Pancreatic Fibrosis and Pancrea- tic Cell Apoptosis Induced by Fas/Fas Ligand Pathways in Aly/Aly Mice

In this study, we examined the relationship between the expression of Fas/Fas ligand apoptotic signaling pathway and pancreatic fibrosis in autoimmune chronic pancreatitis of aly/aly mice. The histopathological changes of inflammatory cell infiltration in pancreatitis aly/ aly mice were observed. Immunohistochemistry was used to detect the expression of CD4, CD8, CD45R/B220, F4, Fas/Fas ligand, collagen …

The Relationship between Pancreatic Fibrosis and Pancrea- tic Cell Apoptosis Induced by Fas/Fas Ligand Pathways in Aly/Aly Mice Read More »

The Endoscopic Combo Technique: Long-Term Outcomes in Treating Patients with Primary Achalasia

Achalasia is a primary esophageal motility disorder characterized by the absence of esophageal peristalsis and impaired relaxation of the Lower Esophageal Sphincter (LES) in response to swallowing. The annual incidence of achalasia is approximately 1.6 per 100,000 individuals worldwide and prevalence of 10 cases per 100,000 individuals. Patients present usually with progressive dysphagia to solids …

The Endoscopic Combo Technique: Long-Term Outcomes in Treating Patients with Primary Achalasia Read More »

Quadruple with Omeprazole, Bismuth, Tetracycline and Metroni- dazole Therapy for the Eradication of Helicobacter Pylori: Efficacy in Naive and Previously Treated Patients with Double and Triple Antimicrobial Resistance

To eradicate Helicobacter Pylori (HP) infection it’s necessary to use at least two antibiotics. In patients infected with HP resistant to two or three antibiotics, eradication is more difficult. The objective of this study was to evaluate the efficacy of bismuth quadruple therapy (BQT)-10 days (omeprazole, bismuth, tetracycline-TET, and metronidazole-MTZ) for the eradication for HP …

Quadruple with Omeprazole, Bismuth, Tetracycline and Metroni- dazole Therapy for the Eradication of Helicobacter Pylori: Efficacy in Naive and Previously Treated Patients with Double and Triple Antimicrobial Resistance Read More »

Direct Acting Antivirals in Hepatitis C Virus Genotype 3 and Advanced Cirrhosis

Direct-Acting Antivirals (DAAs) have revolutionized the management of hepatitis C infection. However, genotype 3 cirrhosis is still difficult to treat. We report our experience in the management of geno- type 3 cirrhosis with DAA’s. We analysed 111 adult cirrhotics with genotype 3 infection of which 54 (48.6%) had Decom- pensated Cirrhosis (DC). Patients with Compensated

HO-1 as a Dynamic Sensor in the Livers of Chronic Cerebral Hypoperfusion Rats

Heme oxygenases, mainly including heme oxygenase-1(HO-1) and heme oxygenase-1(HO-2), play a key role in protecting from oxidative stress and inflammation associated with vascular disease. Little is known, however, about the roles of HO-1 and HO-2 in the livers of rats with chronic cerebral hypo perfusion. The study aims to evaluate the expression and roles of …

HO-1 as a Dynamic Sensor in the Livers of Chronic Cerebral Hypoperfusion Rats Read More »

Does Measured Aggression with Stereotactic Hypo Fractionated Radiotherapy and TACE Allow Liver Transplant in Patients with Hepatocellular Carcinoma with Portal Vein Tumour Thrombus – A Retrospective Study

Patients with liver confined HCC with PVTT and minimum 1000 cc volume of uninvolved cirrhotic liver underwent SHORT and TACE, former administered using Rapid Arc, dose 32-50Gy in 5-14 fractions. TACE was performed using gel foam slurry, Inj. C is platinum and PVA. Liver transplant was performed on radiological evidence of recanalization or conversion to …

Does Measured Aggression with Stereotactic Hypo Fractionated Radiotherapy and TACE Allow Liver Transplant in Patients with Hepatocellular Carcinoma with Portal Vein Tumour Thrombus – A Retrospective Study Read More »

The Effect of Long-Term Human Albumin Administration on the Mortality of Adult Patients with De Compensated Liver Cirrhosis: A Meta-Analysis and Systematic Review

Liver disease accounts for approximately 2 million deaths per year worldwide, 1 million due to complications of cirrhosis. Mortality trends in cirrhosis have been increasing in the Phi- lippines; data from 1990 to 2010 showed that there has been an overall increase of mortality by 53.7%. One of the promising treatment options for patients with …

The Effect of Long-Term Human Albumin Administration on the Mortality of Adult Patients with De Compensated Liver Cirrhosis: A Meta-Analysis and Systematic Review Read More »