1. Abstract 1.1. Introduction: Chronic Hepatitis C Virus (HCV) infection, a leading cause of liver cirrhosis, causes significant morbidity and mortality and has become an important indication for liver transplantation all over the world. The initial treatment was with Pegylated Interferon and Ribavarin but later on wide availability of oral Directly Acting Antiviral (DAA) drugs …
1. Abstract 1.1. Background: Several patient, government, payer, and provider-level barriers to Hepatitis C virus (HCV) treatment have been identified in regions like Asia, Africa, and the Commonwealth of Independent States (CIS). A patient registry was created in these regions to understand the patterns of clinical care and outcomes in real-world settings.
1. Abstract 1.1. Background: Often patients with carcinomas of esophagus presents with dysphagia at a late stage where curative treatments are not a treatment option. To relieve dysphagia and its consequences palliative esophageal stentings are offered. Self-expanding metal stents (SEMS) and self-expanding plastic stents (SEPS) are available for reliving the dysphagia. Uncovered, partially covered, or …
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1. Abstract 1.1. Background: Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) is a transcription factor that regulates the expression of the cellular antioxidant response. Traditionally, Nrf2 is regarded as a tumor suppressor owing to its characteristic which prevents oxidative or electrophilic insult. However, there is increasing evidence that Nrf2 is activated in malignant cells. At …
1. Abstract 1.1. Background: Colorectal cancer liver metastases (CRLM) that cannot be surgically removed are often addressed locally with Hepatic Arterial Infusion (HAI) or Selective Internal Radiation Therapy (SIRT). This study used Bayesian network meta-analysis (NMA) to assess the differences in survival between patients treated with HAI or SIRT for CRLM.
1. Abstract 1.1. Background: Colorectal cancer liver metastases (CRLM) that cannot be surgically removed are often addressed locally with Hepatic Arterial Infusion (HAI) or Selective Internal Radiation Therapy (SIRT). This study used Bayesian network meta-analysis (NMA) to assess the differences in survival between patients treated with HAI or SIRT for CRLM.
1. Abstract 1.1. Background: Anemia represents a significant problem in Inflammatory Bowel Disease (IBD) and diagnosis may be challenging due to inflammation. Hepcidin, ferroportin and hephaestin are novel Iron Regulatory Proteins (IRPs) involved in iron metabolism. This study aimed to identify the interactions of these proteins in IBD patients, guiding safe iron supplementation and effective …
1. Abstract 1.1. Background: Colorectal cancer (CRC) is the third most common and the fourth most lethal type of cancer. Current therapies for CRC mainly include chemotherapy, radiotherapy, and surgery. However, the therapeutic effects of these therapies are not satisfactory for advanced CRC patients.
1. Abstract 1.1. Introduction: Covid-19 is a global pandemic around the world and entered India in March,2020 and has led to substantial morbidity and mortality till date. There had been many drug trials all over world for it but, many time treatment strategies have been revised in different parts of world, including India but still …
1. Abstract 1.1. Background: Yindan Pinggan Capsule, a patent Chinese medicine, has a definite effect on Yang Huang syndrome. At present, the pharmacological activity and quality control of Yindan Pinggan Capsule have been studied, but its effective constituents on the treatment of Yang Huang syndrome are still unclear.
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