Research Article

1. Abstract 1.1. Background and Aim The epidemiology, clinical characteristics, natural course, and treatment of Inflammatory Bowel Disease (IBD) in the gastroenterology centres of Al Kharj, Riyadh Province, are still largely unknown. Therefore, a survey was conducted to describe IBD features to correlate the findings with published data from the rest of the country and …

Inflammatory Bowel Disease in a Central Rural Area, Riyadh Province Al-Kharj of Saudi Arabia: Epidemiology, Clinical Characteristics, Natural Course of Disease and Current Clinical Practice Read More »

1. Abstract 1.1. Background: We evaluated the changes of biomarkers and their significance in patients with nonalcoholic fatty liver disease. 1.2. Methods: One hundred and ten nonalcoholic fatty liver disease patients were enrolled into experimental group and one hundred and ten healthy people into control group. The plasma levels of biomarkers were detected. 1.3. Results: …

Changes of Plasma Biomarkers in Patients with Chronic Liver Diseases Predict Liver Cell Death Read More »

1. Abstract Hepatocyte transplantation for acute liver failure and metabolic liver disorders represent a potential alternative to traditional orthotopic liver transplantation (OLT). Additionally, cultured primary hepatocytes are an important tool for in vitro pharmacological studies. Advances in clinical hepatocyte transplantation and drug studies depend on the development of standardized isolation and culturing protocols as well …

Primary Murine Hepatocyte Isolation and Culture with GMP and Research-Grade Enzyme Blends Read More »

1. Abstract 1.1. Aim: The objective of study reported here was to evaluate the clinical efficacy, side effects and long survival time in the advanced stages of all solid tumors after the treatment of UMIPIC. 1.2. Methods: 581 patients with solid tumors in late stages were collected for retrospect analysis of their clinical efficacy, adverse …

Acute Tumor Inflammation with CD4/8+ and CD11+ Enhanced Long Survival Time in Advanced Stages of all Solid tumors by Ultra Minimum Incision Personalized Intratumoral Chemoimmunotehrapy Read More »

1. Abstract 1.1. Aims: The purpose of this study was to describe Portosystemic Cannulation (PSC) Under Ultrasound (US) guidance to perform a Transjugular Intrahepatic Portosystemic Shunt (TIPS) placement. 1.2. Methods: Medical records of 23 patients who underwent TIPS procedure with US-guided PSC at our institute between October 2018 to December 2021 were reviewed, including for …

Ultrasound-Guided Portosystemic Cannulation During Transjugular Intrahepatic Portosystemic Shunt Placement: An Experience of 23 Cases Read More »

1. Abstract 1.1. Background Endoscopic ultrasonography (EUS) has become a reliable method for predicting the invasion depth of early gastric cancer (EGC). However, diagnostic accuracy of EUS is affected by several factors. In particular, it is difficult to differentiate between T1a and T1b EGC through EUS. The aim of this study was to confirm whether …

Diagnostic Evaluation of Endoscopic Ultrasonography with and without Submucosal Saline Injection for Differentiating Between T1a and T1b Early Gastric Cancer Read More »

1. Abstract 1.1. Background Oncological survival after operation of resectable pancreatic ductal adenocarcinoma (R-PDAC) is variable depending on various factors. Preoperative risk stratification could guide decision-making in multidisciplinary treatment concepts. We develop and validate a prognostic score for disease-free survival (DFS) in R-PDAC to solve this issue.

1. Abstract 1.1. Background and Objetive: Irritable bowel syndrome (IBS) is presented as a biopsychosocial model according to Rome criteria. In Chile there are not studies on psychosocial risk factors (PRF) in IBS. The aim was to evaluate PRF in patients with IBS and their relationship with clinical severity, phenotypes and associated pathologies. 1.2. Methods …

Psychosocial Risk Factors in Chilean Patients with Irritable Bowel Syndrome Read More »

1. Abstract 1.1. Purpose To study the survival time of mice with tumor by intratumoral injection with chemotherapy drug Adr plus hapten of DNP or Hydra and find a combination of drugs of Adr with DNP or Hydra can prolong their life, and which one of DNP or Hydra can provide a long life extension …

Acute Tumor Inflammation with CD4/8+ and CD11+ Prolong The Survival Effect Induced by Intratumral Injection Optimum Combination of Chemotherapy Drugs with Hydralazine as Hapten in Animal Model Read More »

1. Abstract 1. Aims: This study aims to compare the HR-QoL among rural Chinese patients with upper GI diseases at different pathological stages and to determine the factors influencing HR-QoL in this population. 1.2. Methods: A cross-sectional survey was conducted in two counties in Shandong province in China from July to September 2018. Demographic and …

Health-Related Quality of Life Among Rural Chinese Patients with Upper Gastrointestinal Diseases at Different Pathological Stages: A Cross-Sectional Study Read More »