Month: December 2021

Microrna-145 Inhibits EMT and Fibrosarcoma Cell Proliferation, Migration and Invasion by Targeting HMGA2

1. Abstract 1.1 Aim: Fibrosarcoma is a rare malignant tumor of subcutaneous tissue characterized by slow infiltrative growth and a high rate of local recurrence. The participation of microRNAs (miRNAs/miRs) in the pathogenesis of human diseases and the vital role of miR-145 in different types of cancer. However, the role of miR-145 in fibrosarcoma remains …

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Primary Biliary Cholangitis and Type 1 Diabetes in A Male Patient: A Case Report

1. Abstract Primary Biliary Cholangitis (PBC) isa cholestatic disease of autoimmune origin characterized by the destruction of small to medium size intrahepatic bile ducts due to lymphocytic infiltration. The diagnosis is made by the presence of Anti-Mitochondrial Antibodies (AMAs) specific for the disease. PBC typically affects middle-aged women and is often associated with other autoimmune …

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Pseudotumoral Form of Primary Hepatic Tuberculosis: A Rare Case Report with Review of the Literature

1. Abstract The isolated location of tuberculosis is very rare constituting less than 1% of all locations. We report through this observation the case of a 23-year-old patient, who complains of chronic pain in the right hypochondrium in a context of deterioration of the general condition. The biological assessment showed a biological inflammatory syndrome. A …

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Comparing The Efficacy and Safety of Local-Regional Treatments for Hepatocellular Carcinoma with Portal/Hepatic Vein Tumor Thrombosis in China: A Network Meta-Analysis of Randomized Control Trials

1. Abstract 1.1. Purpose: We assessed the efficacy and safety of different local-regional regimens using the network metaanalysis for hepatocellular carcinoma (HCC) with portal/hepatic vein tumor thrombosis. The interested modalities included neoadjuvant three-dimensional radiotherapy(3D-CRT), postoperative intensity-modulated radiation therapy(IMRT), Postoperative transarterial chemoembolization (TACE), 3DCRT plus TACE, and Surgery alone.

Clinical Approach to Diarrhea in Long Term Care Hospitals

1. Clinical Approach to Diarrhea in Long Term Care Hospitals Diarrhea is common in long term care hospitals but at many times get underdiagnosed. Symptomatic treatment of diarrhea is sometimes effective but tends to relapse after treatment is seized and also side effects are seen. The root cause of diarrhea must be evaluated in order …

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Fecal Calprotectin in Children Can Differentiate between Different Gastrointestinal Diseases

1. Abstract 1.1. Background: Fecal calprotectin (FC) is increased in gastrointestinal inflammation due to increased permeability of the gastrointestinal mucosa. It could be used to differentiate between different gastrointestinal disorders. 1.2. Purpose: The aim of the present study was to examine the relationship between fecal calprotectin and different pediatric gastrointestinal diseases and to investigate if …

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Three Different Presentations of Metastatic Gastric Melanoma

1. Abstract Melanoma is the most common metastatic tumor of the gastrointestinal (GI) tract and its diagnosis is rare during life since its symptoms are non-specific. The endoscopic gastric metastases appearance is heterogenous with no typical pattern. We report a patient who presented three different morphologies of metastatic gastric melanoma although the patient remained asymptomatic. …

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Effect of Antibiotics on The Gut Microbiota in Children with Chronic Pancreatitis

1. Abstract 1.1. Objectives: Little is known about the effect of antibiotic treatment on the gut microbiota in children with chronic pancreatitis (CCP). Our objective was to identify the effect of antibiotic treatment on the gut microbiota in children with chronic pancreatitis (CCP), the main gut microbiota genera and characterize the patients’ functional mutations after …

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